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A non-conserved miRNA regulates lysosomal function and impacts on a human lysosomal storage disorder

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  1. Article

    Open Access

    Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution

    Dynamic change in subcellular localization of signaling proteins is a general concept that eukaryotic cells evolved for eliciting a coordinated response to stimuli. Mass spectrometry-based proteomics in combin...

    Ana Martinez-Val, Dorte B. Bekker-Jensen, Sophia Steigerwald… in Nature Communications (2021)

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  2. Article

    Open Access

    Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites

    The centrosome is the master orchestrator of mitotic spindle formation and chromosome segregation in animal cells. Centrosome abnormalities are frequently observed in cancer, but little is known of their origi...

    Søs Grønbæk Holdgaard, Valentina Cianfanelli, Emanuela Pupo… in Nature Communications (2019)

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