39 Result(s)
within
Lino Nobili
English
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Article
Open AccessEuropean expert guidance on management of sleep onset insomnia and melatonin use in typically develo** children
Slee** problems are prevalent among children and adolescents, often leading to frequent consultations with pediatricians. While cognitive-behavioral therapy has shown effectiveness, especially in the short t...
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Article
Brain and spine malformations and neurodevelopmental disorders in a cohort of children with CAKUT
Congenital anomalies of the kidney and urinary tract (CAKUT) represent 20–30% of all birth defects and are often associated with extra-renal malformations. We investigated the frequency of brain/spine malforma...
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Article
Surgical treatment of cavernous malformation-related epilepsy in children: case series, systematic review, and meta-analysis
Objective: Cerebral cavernous malformations (CCMs) are cerebral vascular lesions that occasionally occur with seizures. We present a retrospective case series from IRCCS Gaslini Children’s Hospital, a systematic ...
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Article
Evaluation and management of insomnia in the clinical practice in Italy: a 2023 update from the Insomnia Expert Consensus Group
Insomnia is the most reported sleep disorder in industrialized countries, affecting, in the chronic form, around 10% of the European population. In Italy, such a percentage seems to be even higher. Although in...
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Article
Open AccessNLP-based tools for localization of the epileptogenic zone in patients with drug-resistant focal epilepsy
Epilepsy surgery is an option for people with focal onset drug-resistant (DR) seizures but a delayed or incorrect diagnosis of epileptogenic zone (EZ) location limits its efficacy. Seizure semiological manifes...
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Article
Acute pediatric encephalitis: etiology, course, and outcome of a 12-year single-center immunocompetent cohort
Encephalitis is an uncommon but severe disorder due to an inflammation of the brain parenchyma, usually diagnosed on clinical, laboratory, electroencephalographic, and neuroradiological features. New causes of...
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Article
Open AccessBrain criticality predicts individual levels of inter-areal synchronization in human electrophysiological data
Neuronal oscillations and their synchronization between brain areas are fundamental for healthy brain function. Yet, synchronization levels exhibit large inter-individual variability that is associated with be...
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Article
Correction to: Insomnia in Children with Autism Spectrum Disorder: A Cross-Sectional Study on Clinical Correlates and Parental Stress
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Chapter
Sleep and Epilepsy
Sleep and epilepsy have a mutual connection. Sleep may activate interictal epileptiform discharges (IEDs) and/or trigger seizures. Comorbid sleep-related disorders which chronically induce sleep fragmentation ...
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Article
Insomnia in primary care: a survey conducted on Italian patients older than 50 years—results from the “Sonno e Salute” study
Insomnia affects one-third of the adult population and is associated with multiple medical conditions. We conducted an observational epidemiological survey to assess (1) the prevalence of insomnia in an Italia...
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Article
Imaging characteristics and neurosurgical outcome in subjects with agenesis of the corpus callosum and interhemispheric cysts
To explore the relationships between clinical-radiological features and surgical outcomes in subjects with interhemispheric cysts (IHC) and corpus callosum anomalies.
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Article
Open AccessClinical characteristics of a large cohort of patients with narcolepsy candidate for pitolisant: a cross-sectional study from the Italian PASS Wakix® Cohort
Narcolepsy is a chronic and rare hypersomnia of central origin characterized by excessive daytime sleepiness and a complex array of symptoms as well as by several medical comorbidities. With growing pharmacolo...
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Article
Open AccessCorrection to: Sleep disturbances in craniopharyngioma: a challenging diagnosis
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Article
Open AccessSleep disturbances in craniopharyngioma: a challenging diagnosis
Craniopharyngiomas are rare solid or mixed solid and cystic tumors that arise from Rathke’s pouch remnants along the pituitary-hypothalamic axis, from the sella turcica to the brain third ventricle. Both the t...
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Article
Open AccessIdentifying the signature of prospective motor control in children with autism
Failure to develop prospective motor control has been proposed to be a core phenotypic marker of autism spectrum disorders (ASD). However, whether genuine differences in prospective motor control permit discri...
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Chapter
Sleep-Related Epilepsy, Dysautonomia, and Sudden Nocturnal Death
Sleep and epilepsy have an intimate relationship. Some epilepsy syndromes are characterized by seizures occurring mostly or exclusively during sleep or on awakening. Many studies have reported autonomic change...
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Article
Open AccessSimultaneous human intracerebral stimulation and HD-EEG, ground-truth for source localization methods
Precisely localizing the sources of brain activity as recorded by EEG is a fundamental procedure and a major challenge for both research and clinical practice. Even though many methods and algorithms have been...
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Chapter and Conference Paper
Classification of Epileptic Activity Through Temporal and Spatial Characterization of Intracranial Recordings
Focal epilepsy is a chronic condition characterized by hyper-activity and abnormal synchronization of a specific brain region. For pharmacoresistant patients, the surgical resection of the critical area is con...
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Article
Cerebral blood flow in a case of typical aura without headache
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Article
Prognostic factors of postoperative seizure outcome in patients with temporal lobe epilepsy and normal magnetic resonance imaging
To retrospectively analyse a single-centre consecutive surgical series of patients with temporal lobe epilepsy (TLE) and negative MRI. To identify factors associated with postoperative seizure outcome among se...
