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3,060 Result(s)
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Article
Open AccessNOX4-mediated astrocyte ferroptosis in Alzheimer’s disease
This study investigates NADPH oxidase 4 (NOX4) involvement in iron-mediated astrocyte cell death in Alzheimer’s Disease (AD) using single-cell sequencing data and transcriptomes. We analyzed AD single-cell RNA...
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Retraction Note: How green finance reduces CO2 emissions for green economic recovery: empirical evidence from E7 economies
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Tissue-resident C1q + macrophages exert anti-aging potential through the Sirt1 pathway
Resident immune cells are at the forefront of sensory organ-specific signals, and changes in these cells are closely related to the aging process. The Sirt pathway can regulate NAD + metabolism during aging, t...
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Clinical characteristics of systemic lupus erythematosus patients with adrenal hemorrhage
Adrenal hemorrhage (AH) is a rare condition and severe cases can lead to acute adrenal insufficiency with potentially life-threatening consequences. AH can be caused by a variety of etiologic factors, includin...
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Associations between atherosclerotic luminal stenosis in the distal internal carotid artery and diffuse wall thickening in its upstream segment
Significant atherosclerotic stenosis or occlusion in the distal internal carotid artery (ICA) may induce diffuse wall thickening (DWT) in the upstream arterial wall. This study aimed to assess the association ...
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Towards an assessment model of college students’ computational thinking with text-based programming
Computational thinking (CT) assessment is crucial for testing the effectiveness of CT skills development. However, the exploration of CT assessment in the context of text-based programming is in its initial st...
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Effects of behaviors and surrounding environment on myopia before and during the COVID-19 pandemic: a longitudinal analysis of children and adolescents in China
To investigate the relationship between related factors and visual acuity of Chinese school students before and during the COVID-19 pandemic.
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Open AccessCTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment
The three-dimensional genome structure organized by CTCF is required for development. Clinically identified mutations in CTCF have been linked to adverse developmental outcomes. Nevertheless, the underlying mecha...
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A robust visual SLAM system for low-texture and semi-static environments
Precisely estimating a vehicle’s pose in a prior map is a fundamental capability for autonomous driving. This task, however, remains challenging in low-texture and semi-static environments where the number of ...
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A dynamic spectrum access algorithm based on deep reinforcement learning with novel multi-vehicle reward functions in cognitive vehicular networks
As a revolution in the field of transportation, the demand for communication of vehicles is increasing. Therefore, how to improve the success rate of vehicle spectrum access has become a major problem to be so...
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Development of a label-free photoelectrochemical immunosensor for novel astrovirus detection
Since 2017, an infectious goose gout disease characterized by urate precipitation in viscera, mainly caused by novel goose astrovirus (GoAstV) infection, has emerged in the main goose-producing region of China...
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Preparation of bacterial fertilizer from biogas residue after anaerobic co-digestion of kitchen waste and residual sludge
Azotobacter chroococcum and Bacillus subtilis were selected as fermentation strains, and biogas residue after anaerobic digestion of kitchen waste and residual sludge was used as fermentation substrate. A single ...
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PID4LaTe: a physics-informed deep learning model for lake multi-depth temperature prediction
Lake temperature plays a pivotal role in the physical and chemical processes in the water. It has a significant impact on the distribution of lake organisms. In lake temperature modelling, the physics-based mo...
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Optimization of Deamidation of Casein by Protein-Glutaminase and Its Effect on Structural and Functional Properties
Casein is a commonly used protein in the food industry, with its related products such as beverages and desserts. However, the further application of casein is limited by its solubility and stability. This stu...
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Highly efficient degradation of tetracycline in groundwater by nanoscale zero-valent iron-copper bimetallic biochar: active [H] attack and direct electron transfer mechanism
Development of carbon materials with high activity was important for rapid degradation of emerging pollutants. In this paper, a novel nanoscale zero-valent iron-copper bimetallic biochar (nZVIC-BC) was synthes...
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Open AccessDNAJC1 facilitates glioblastoma progression by promoting extracellular matrix reorganization and macrophage infiltration
Glioblastoma (GBM) is a high-grade and heterogeneous subtype of glioma that presents a substantial challenge to human health, characterized by a poor prognosis and low survival rates. Despite its known involve...
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Open AccessMandelonitrile lyase MDL2-mediated regulation of seed amygdalin and oil accumulation of Prunus Sibirica
The Prunus sibirica seeds with rich oils has great utilization, but contain amygdalin that can be hydrolyzed to release toxic HCN. Thus, how to effectively reduce seed amygdalin content of P. sibirica is an inter...
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Open AccessAdoption of the cardiopulmonary exercise test in the exercise ability and cardiopulmonary function rehabilitation of coronary artery disease (CAD) patients
This study aimed to explore the application of cardiopulmonary exercise testing in coronary artery disease (CAD) patients, evaluate its impact on exercise ability and cardiopulmonary function in patients with ...
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Open AccessRisk factors for subsequent suicidal acts among 12–25-year-old high-risk callers to a suicide prevention hotline in China: a longitudinal study
A few previous cross-sectional studies investigated correlated factors of suicidal ideation or suicide attempts among suicide prevention hotline callers; however, scarcely any evidence was from a longitudinal ...
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Bogdanov–Takens bifurcation of an enzyme-catalyzed reaction model
Enzyme-catalyzed reactions are frequently observed in the chemical process, and could be described by the mathematical model, such as the Gray–Scott model with Langmuir–Hinshelwood mechanism. The complex dynam...