-
Article
Open AccessThe architecture of substrate-engaged TOM–TIM23 supercomplex reveals preprotein proximity sites for mitochondrial protein translocation
-
Article
Open AccessMeckel’s diverticulum mimicking acute appendicitis in children: a retrospective cohort study
The aims of this study were to summarize the clinical presentation and histological results of 20 cases of complicated Meckel diverticulum (MD) who were presumed to have acute appendicitis before surgery, as w...
-
Article
Open AccessConstruction and validation of a competency model for hospital operation assistant of public hospitals in China: a cross‑sectional study
Hospital operation assistant (HOA) plays an important role in promoting the operation effectiveness and efficiency of hospital. China, as a resource-poor country, urgently needs to train HOA talent. The purpos...
-
Article
Open AccessCSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages
Microglia are known to regulate stress and anxiety in both humans and animal models. Psychosocial stress is the most common risk factor for the development of schizophrenia. However, how microglia/brain macrop...
-
Article
Open AccessComparison of partial nephrectomy and radical nephrectomy for cystic renal cell carcinoma: a SEER-based and retrospective study
Cystic renal cell carcinoma (cRCC) is uncommon and surgical indication remains controversial. We compared radical nephrectomy (RN) with partial nephrectomy (PN) in patients with cRCC using data from the Survei...
-
Article
Open AccessThe dynamic changes of HBV quasispecies diversity in infancy after immunoprophylaxis failure: a prospective cohort study
Previous works have observed that younger infants with chronic hepatitis B virus (HBV) infection are more responsive to antiviral treatment. However, the underlying mechanism remains unclear. In this study, th...
-
Article
Open AccessRapid detection of avian leukosis virus subgroup J by cross-priming amplification
Avian leukosis virus subgroup J (ALV-J) causes oncogenic disease in chickens in China, resulting in great harm to poultry production, and remains widespread in China. Herein, we employed a cross-priming amplif...
-
Article
Open AccessStructural insights into assembly of human mitochondrial translocase TOM complex
-
Article
Open AccessPrognostic value of Glypican family genes in early-stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy and possible mechanisms
This study explored the prognostic significance of Glypican (GPC) family genes in patients with pancreatic ductal adenocarcinoma (PDAC) after pancreaticoduodenectomy using data from The Cancer Genome Atlas (TC...
-
Article
Open AccessThe value of L3 skeletal muscle index in evaluating preoperative nutritional risk and long-term prognosis in colorectal cancer patients
L3 skeletal muscle index (L3SMI) was reportedly related to postoperative outcomes. We aimed to investigate the value of L3SMI in evaluating preoperative nutritional risk and long-term prognosis in colorectal c...
-
Article
Open AccessStructural basis of tubulin detyrosination by VASH2/SVBP heterodimer
The C-terminus of α-tubulin undergoes a detyrosination/tyrosination cycle and dysregulation of this cycle is associated with cancer and other diseases. The molecular mechanisms of tubulin tyrosination are well...
-
Article
Open AccessLncRNA PVT1 regulates atrial fibrosis via miR-128-3p-SP1-TGF-β1-Smad axis in atrial fibrillation
Long non-coding RNAs (lncRNA) plasmacytoma variant translocation 1 (PVT1) has been shown to be associated with liver fibrosis. Nevertheless, the role of PVT1 in atrial fibrosis remains undefined. This study ai...
-
Article
Open AccessThe health service capacity of primary health care in West China: different perspectives of physicians and their patients
Many countries, including China, have identified the primary health care system as a reform priority. The purpose of this study is to compare the perceived service capacity of primary care from the perspective...
-
Article
Erratum to: Disruption of mindin exacerbates cardiac hypertrophy and fibrosis
-
Article
Open AccessOveruse of antibiotics for the common cold – attitudes and behaviors among doctors in rural areas of Shandong Province, China
Irrational antibiotic use is common in rural areas of China, despite the growing recognition of the importance of appropriate prescribing to contain antibiotic resistance. The aim of this study was to analyze ...
-
Article
Open AccessHyperbaric oxygen therapy in China
Hyperbaric oxygen therapy (HBOT) is defined as a treatment in which a patient intermittently breathes 100% oxygen while the treatment chamber is pressurized to a pressure greater than sea level (1.0 atmosphere...
-
Article
Open AccessA type-specific nested PCR assay established and applied for investigation of HBV genotype and subgenotype in Chinese patients with chronic HBV infection
Many studies have suggested that hepatitis B virus (HBV) genotypes show not only geographical distribution and race specificity, but also are associated with disease progression and response to interferon trea...
-
Chapter and Conference Paper
Displacement Template with Divide-&-Conquer Algorithm for Significantly Improving Descriptor Based Face Recognition Approaches
This paper proposes a displacement template structure for improving descriptor based face recognition approaches. With this template structure, a face is represented by a template consisting of a set of piled ...
-
Article
Open AccessThermal stability and inactivation of hepatitis C virus grown in cell culture
Hepatitis C virus (HCV) is a blood-borne flavivirus that infects many millions of people worldwide. Relatively little is known, however, concerning the stability of HCV and reliable procedures for inactivating...
-
Article
Changes in Glial Cell Line-derived Neurotrophic Factor Expression in the Rostral and Caudal Stumps of the Transected Adult Rat Spinal Cord