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    Leukocyte immunoglobulin-like receptor B4 protects against cardiac hypertrophy via SHP-2-dependent inhibition of the NF-κB pathway

    Cardiac hypertrophy is a complex pathological process, and the molecular mechanisms underlying hypertrophic remodeling have not been clearly elucidated. Leukocyte immunoglobulin-like receptor B4 (lilrb4) is an...

    Heng Zhou, Ning Li, Yuan Yuan, Ya-Ge **, Qingqing Wu in Journal of Molecular Medicine (2020)

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    Effect of maternal and embryonic factors on frozen-thawed IVF-ET outcome after pre-equilibration with hyaluronan

    To systematically evaluate the effect of maternal and embryonic factors on in vitro fertilization and embryo transfer (IVF-ET) outcomes among Chinese patients after using hyaluronan-enriched transfer medium (H...

    Weizhou Wang, Likun Ren, Deli Wei, Yuliang Shen in Archives of Gynecology and Obstetrics (2019)

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    Erratum to: Disruption of mindin exacerbates cardiac hypertrophy and fibrosis

    Zhou-Yan Bian, **ang Wei, Shan Deng, Qi-Zhu Tang in Journal of Molecular Medicine (2017)

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    Disruption of mindin exacerbates cardiac hypertrophy and fibrosis

    Cardiac hypertrophy is a response of the myocardium to increased workload and is characterised by an increase of myocardial mass and an accumulation of extracellular matrix (ECM). As an ECM protein, an integri...

    Zhou-Yan Bian, **ang Wei, Shan Deng, Qi-Zhu Tang in Journal of Molecular Medicine (2012)

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    Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3β signaling

    The lysosomal cysteine peptidase cathepsin L (CTSL) is an important lysosomal proteinase involved in a variety of cellular functions including intracellular protein turnover, epidermal homeostasis, and hair de...

    Qizhu Tang, Jun Cai, Difei Shen, Zhouyan Bian, Ling Yan in Journal of Molecular Medicine (2009)

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    Inactivated MGMT by O6-Benzylguanine is associated with prolonged G2/M arrest in cancer cells treated with BCNU

    HCT116 and HCT15 cells that highly express O6-methylguanine-DNA-methyltransferase (MGMT) displayed a transient cell cycle G2/M arrest in response to exposure to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) alone; ...

    Ling Yan, Jon R Donze, Lili Liu in Oncogene (2005)