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Article
Contrast CT radiomic features add value to prediction of prognosis in adrenal cortical carcinoma
Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with poor prognosis due to high postoperative recurrence rates. The aim of this study is to develop a contrast CT radiomic feature-based progn...
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Article
Open AccessMeckel’s diverticulum mimicking acute appendicitis in children: a retrospective cohort study
The aims of this study were to summarize the clinical presentation and histological results of 20 cases of complicated Meckel diverticulum (MD) who were presumed to have acute appendicitis before surgery, as w...
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Article
Open AccessConstruction and validation of a competency model for hospital operation assistant of public hospitals in China: a cross‑sectional study
Hospital operation assistant (HOA) plays an important role in promoting the operation effectiveness and efficiency of hospital. China, as a resource-poor country, urgently needs to train HOA talent. The purpos...
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Article
Open AccessCSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages
Microglia are known to regulate stress and anxiety in both humans and animal models. Psychosocial stress is the most common risk factor for the development of schizophrenia. However, how microglia/brain macrop...
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Article
A qualitative research exploring the experiences of patients receiving immune checkpoint inhibitors for advanced lung cancer
In patients with advanced lung cancer, immune checkpoint inhibitors (ICIs) dramatically extended survival. We aimed to investigate the experiences of patients with advanced lung cancer who are receiving ICIs, ...
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Article
Clinicopathologic and prognostic factors for colorectal cancer in children and adolescents: a population-based study
Colorectal cancer (CRC) is rarely found in children and adolescents. The purpose of this study was to retrospectively conduct a population-based cohort of pediatric patients with CRC.
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Article
Brain Activation Site of Laryngeal Elevation During Swallowing: An fMRI Study
The object of this study is to investigate dysphagia caused by reduced laryngeal elevation in patients poststroke. The central mechanism of laryngeal elevation during swallowing was explored by comparing the b...
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Article
Open AccessPrognostic value of Glypican family genes in early-stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy and possible mechanisms
This study explored the prognostic significance of Glypican (GPC) family genes in patients with pancreatic ductal adenocarcinoma (PDAC) after pancreaticoduodenectomy using data from The Cancer Genome Atlas (TC...
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Article
The prognostic value of combined tumor markers and systemic immune-inflammation index in colorectal cancer patients
This study evaluated the significance of combining tumor markers (TM) and systemic immune-inflammation index (SII) for postoperative complications and long-term outcomes in colorectal cancer (CRC) patients.
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Article
Open AccessThe health service capacity of primary health care in West China: different perspectives of physicians and their patients
Many countries, including China, have identified the primary health care system as a reform priority. The purpose of this study is to compare the perceived service capacity of primary care from the perspective...
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Article
Effect of maternal and embryonic factors on frozen-thawed IVF-ET outcome after pre-equilibration with hyaluronan
To systematically evaluate the effect of maternal and embryonic factors on in vitro fertilization and embryo transfer (IVF-ET) outcomes among Chinese patients after using hyaluronan-enriched transfer medium (H...
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Article
Preparation of a biphase composite scaffold and its application in tissue engineering for femoral osteochondral defects in rabbits
Three-dimensional bioactive scaffolds are useful tools for stem cell implant in tissue-engineering. For chondral and subchondral repair, the chondroinductive and osteoinductive property of a scaffold is a majo...
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Article
Open AccessHyperbaric oxygen therapy in China
Hyperbaric oxygen therapy (HBOT) is defined as a treatment in which a patient intermittently breathes 100% oxygen while the treatment chamber is pressurized to a pressure greater than sea level (1.0 atmosphere...
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Article
Recurrence in giant cell tumour of bone: imaging features and risk factors
This study was done to investigate X-ray, computed tomography (CT) and magnetic resonance (MR) imaging features of recurrence in giant cell tumour of bone (GCTB) and to evaluate risk factors.
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Article
Interferon regulatory factor 3 is a negative regulator of pathological cardiac hypertrophy
Interferon regulatory factor (IRF) 3, a member of the highly conserved IRF family transcription factors, plays a pivotal role in innate immune response, apoptosis, and oncogenesis. Recent studies have implicat...
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Article
Cellular FLICE-inhibitory protein protects against cardiac remodelling after myocardial infarction
Cellular FLICE-inhibitory protein (cFLIP) is a member of the tumour necrosis factor signalling pathway and a regulator of apoptosis, and it has a role in cardiac remodelling following myocardial infarction (MI...
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Article
Rehabilitation effect of systematic exercise on breast cancer patients after adjuvant chemotherapy
To investigate the rehabilitation effect of systematic exercise on breast cancer patients after adjuvant chemotherapy.
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Article
Inactivated MGMT by O6-Benzylguanine is associated with prolonged G2/M arrest in cancer cells treated with BCNU
HCT116 and HCT15 cells that highly express O6-methylguanine-DNA-methyltransferase (MGMT) displayed a transient cell cycle G2/M arrest in response to exposure to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) alone; ...