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Inactivated MGMT by O6-Benzylguanine is associated with prolonged G2/M arrest in cancer cells treated with BCNU
HCT116 and HCT15 cells that highly express O6-methylguanine-DNA-methyltransferase (MGMT) displayed a transient cell cycle G2/M arrest in response to exposure to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) alone; ...