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Inactivated MGMT by O⁶-Benzylguanine is associated with prolonged G₂/M arrest in cancer cells treated with BCNU

HCT116 and HCT15 cells that highly express O⁶-methylguanine-DNA-methyltransferase (MGMT) displayed a transient cell cycle G2/M arrest in response to exposure to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) alone; ...

Ling Yan, Jon R Donze, Lili Liu in Oncogene (2005)