12 Result(s)
-
Article
Open AccessBrain MRI features of methylmalonic acidemia in children: the relationship between neuropsychological scores and MRI findings
Methylmalonic acidemia (MMA) is a severe, heterogeneous disorder of methylmalonate and cobalamin (cbl; vitamin B12) metabolism with a poor prognosis that can cause brain damage. Identifying the magnetic resona...
-
Article
Open AccessSatb1 integrates DNA binding site geometry and torsional stress to differentially target nucleosome-dense regions
The Satb1 genome organizer regulates multiple cellular and developmental processes. It is not yet clear how Satb1 selects different sets of targets throughout the genome. Here we have used live-cell single mol...
-
Article
Open AccessA reference-grade wild soybean genome
Efficient crop improvement depends on the application of accurate genetic information contained in diverse germplasm resources. Here we report a reference-grade genome of wild soybean accession W05, with a fin...
-
Article
Open AccessPopulation genomics of finless porpoises reveal an incipient cetacean species adapted to freshwater
Cetaceans (whales, dolphins, and porpoises) are a group of mammals adapted to various aquatic habitats, from oceans to freshwater rivers. We report the sequencing, de novo assembly and analysis of a finless po...
-
Article
Open AccessGekko japonicus genome reveals evolution of adhesive toe pads and tail regeneration
Reptiles are the most morphologically and physiologically diverse tetrapods, and have undergone 300 million years of adaptive evolution. Within the reptilian tetrapods, geckos possess several interesting featu...
-
Article
Erratum: Camelid genomes reveal evolution and adaptation to desert environments
Nature Communications 5:5188; doi: 10.1038/ncomms6188 (2014); Published 21 Oct 2014; Updated 28 Jan 2015 In this Article Junyi Wang is incorrectly listed as one of several equally contributing authors. The cor...
-
Article
Camelid genomes reveal evolution and adaptation to desert environments
Bactrian camel (Camelus bactrianus), dromedary (Camelus dromedarius) and alpaca (Vicugna pacos) are economically important livestock. Although the Bactrian camel and dromedary are large, typically arid-desert-ada...
-
Article
Open AccessThe Brassica oleracea genome reveals the asymmetrical evolution of polyploid genomes
Polyploidization has provided much genetic variation for plant adaptive evolution, but the mechanisms by which the molecular evolution of polyploid genomes establishes genetic architecture underlying species d...
-
Article
Erratum: High genome heterozygosity and endemic genetic recombination in the wheat stripe rust fungus
Nature Communications 4: Article number: 2673 (2013); Published: 23 October 2013; Updated: 29 January 2014. The original version of this Article contained an error in the accession codes section, which specifi...
-
Article
Open AccessHigh genome heterozygosity and endemic genetic recombination in the wheat stripe rust fungus
Stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is one of the most destructive diseases of wheat. Here we report a 110-Mb draft sequence of Pst isolate CY32, obtained using a ‘fosmid-to-fosmid’ ...
-
Article
Open AccessThe tiger genome and comparative analysis with lion and snow leopard genomes
Tigers and their close relatives (Panthera) are some of the world’s most endangered species. Here we report the de novo assembly of an Amur tiger whole-genome sequence as well as the genomic sequences of a white ...
-
Article
Open AccessAscaris suum draft genome
The genome of the common roundworm Ascaris suum, a major parasite in many parts of the world, has now been sequenced. Analyses reveal many genes that encode peptidases linked to the penetration and degradation of...
