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Article
Open AccessEffect of manual OCTA segmentation correction to improve image quality and visibility of choroidal neovascularization in AMD
In this retrospective case series on neovascular age-related macular degeneration (nAMD), we aimed to improve Choroidal Neovascularization (CNV) visualization in Optical Coherence Tomography Angiography (OCTA)...
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Open AccessAuthor Correction: Vaccination induces broadly neutralizing antibody precursors to HIV gp41
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Article
Open AccessTranscriptomic analysis reveals the regulatory mechanisms of messenger RNA (mRNA) and long non-coding RNA (lncRNA) in response to waterlogging stress in rye (Secale cereale L.)
Waterlogging stress (WS) negatively impacts crop growth and productivity, making it important to understand crop resistance processes and discover useful WS resistance genes. In this study, rye cultivars and w...
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Article
Open AccessGlobal, regional, and national burden and trends of migraine among women of childbearing age from 1990 to 2021: insights from the Global Burden of Disease Study 2021
Migraine, a neurological disorder with a significant female predilection, is the leading cause of disability-adjusted life years (DALYs) in women of childbearing age (WCBA). There is currently a lack of compre...
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Article
Open AccessA static precise single-point positioning method based on carrier phase zero-baseline self-differencing
Satellite navigation positioning has become an indispensable component of everyday life, where precise pinpointing and rapid convergence are crucial in delivering timely and accurate location information. Howe...
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Article
Open AccessVaccination induces broadly neutralizing antibody precursors to HIV gp41
A key barrier to the development of vaccines that induce broadly neutralizing antibodies (bnAbs) against human immunodeficiency virus (HIV) and other viruses of high antigenic diversity is the design of primin...
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Article
Open AccessFiring feature-driven neural circuits with scalable memristive neurons for robotic obstacle avoidance
Neural circuits with specific structures and diverse neuronal firing features are the foundation for supporting intelligent tasks in biology and are regarded as the driver for catalyzing next-generation artifi...
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Article
Open AccessDeep learning system for malignancy risk prediction in cystic renal lesions: a multicenter study
To develop an interactive, non-invasive artificial intelligence (AI) system for malignancy risk prediction in cystic renal lesions (CRLs).
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Open AccessViews of Hong Kong Chinese medicine practitioners on the application of the “Chinese Medicine Anti-epidemic Plans” prepared by the Chinese medicine expert group of central authorities: a focus group study
Drawing on the extensive utilization of traditional Chinese medicine (TCM) to combat COVID-19 in Mainland China, experts designed a series of TCM anti-epidemic strategies. This study aims to understand Hong Ko...
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Open AccessA psychometric assessment of a novel scale for evaluating vaccination attitudes amidst a major public health crisis
Despite abundant scientific evidence supporting immunization benefits, vaccine hesitancy remains a significant global health concern, particularly during public health crises. Exploring public attitudes toward...
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Open AccessEfficacy and safety of bispecific antibodies vs. immune checkpoint blockade combination therapy in cancer: a real-world comparison
Emerging tumor immunotherapy methods encompass bispecific antibodies (BSABs), immune checkpoint inhibitors (ICIs), and adoptive cell immunotherapy. BSABs belong to the antibody family that can specifically rec...
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Open AccessDSCAM-AS1 promotes the development of prostate cancer
The purpose of this study was to investigate the role of lncRNA DSCAM-AS1 in prostate cancer to find new therapeutic targets and promote the research progress of prostate cancer.
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Article
Open AccessUltra-wide field and new wide field composite retinal image registration with AI-enabled pipeline and 3D distortion correction algorithm
This study aimed to compare a new Artificial Intelligence (AI) method to conventional mathematical war** in accurately overlaying peripheral retinal vessels from two different imaging devices: confocal scann...
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Open AccessAn automated ICU agitation monitoring system for video streaming using deep learning classification
To address the challenge of assessing sedation status in critically ill patients in the intensive care unit (ICU), we aimed to develop a non-contact automatic classifier of agitation using artificial intellige...
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Article
Open AccessCharacteristics, treatments, in-hospital and long-term outcomes among inpatients with acute exacerbation of chronic obstructive pulmonary disease in China: sex differences in a large cohort study
Data related to the characteristics, treatments and clinical outcomes of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) patients in China are limited, and sex differences are still a negl...
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Article
Open AccessIdentification of chromosomal abnormalities in miscarriages by CNV-Seq
The primary object of this study is to analyze chromosomal abnormalities in miscarriages detected by copy number variants sequencing (CNV-Seq), establish potential pathways or genes related to miscarriages, an...
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Article
Open AccessGlucosylglycerol phosphorylase, a potential novel pathway of microbial glucosylglycerol catabolism
Glucosylglycerol (GG) is a natural compatible solute that can be synthesized by many cyanobacteria and a few heterotrophic bacteria under high salinity conditions. In cyanobacteria, GG is synthesized by GG-pho...
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Open AccessSingle dose recombinant VSV based vaccine elicits robust and durable neutralizing antibody against Hantaan virus
Hantaan virus (HTNV) is a pathogenic orthohantavirus prevalent in East Asia that is known to cause hemorrhagic fever with severe renal syndrome (HFRS), which has a high fatality rate. However, a Food and Drug ...
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Open AccessA simple clinical risk score (ABCDMP) for predicting mortality in patients with AECOPD and cardiovascular diseases
The morbidity and mortality among hospital inpatients with AECOPD and CVDs remains unacceptably high. Currently, no risk score for predicting mortality has been specifically developed in patients with AECOPD a...
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Open AccessThe beneficial endophytic microbes enhanced tobacco defense system to resist bacterial wilt disease
The vital role of rhizosphere microbiome in protecting plants against pathogen infection has been well characterized. By contrast, beneficial effects of the plant endophytic microbiome and interactions with pl...
