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Article
Open AccessMSC-derived exosomes protect auditory hair cells from neomycin-induced damage via autophagy regulation
Sensorineural hearing loss (SNHL) poses a major threat to both physical and mental health; however, there is still a lack of effective drugs to treat the disease. Recently, novel biological therapies, such as ...
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Article
Construction of Non-infectious SARS-CoV-2 Replicons and Their Application in Drug Evaluation
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a devastating pandemic worldwide. Vaccines and antiviral drugs are the most promising candidates for combating this global epidemic, and ...
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Article
Open AccessSARS-CoV-2 nsp12 attenuates type I interferon production by inhibiting IRF3 nuclear translocation
SARS-CoV-2 is the pathogenic agent of COVID-19, which has evolved into a global pandemic. Compared with some other respiratory RNA viruses, SARS-CoV-2 is a poor inducer of type I interferon (IFN). Here, we rep...
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Article
Functional analysis of PGI1 and ZWF1 in thermotolerant yeast Kluyveromyces marxianus
Glycolysis and the pentose phosphate pathway (PPP) are two basic metabolic pathways that are simultaneously present in yeasts. As the main pathway in most species, the glycolysis provides ATP and NADH for cell...
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Article
Simultaneous Analysis of Tocopherols, Phytosterols, and Squalene in Vegetable Oils by High-Performance Liquid Chromatography
Vegetable oils are a rich source of bioactive substances. The non-saponifiable substances that accompany lipids include tocopherols, sterols, squalene. The aim of this study was to develop a new method for the...