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    Effects of Fibroblast Growth Factor 21 on Lactate Uptake and Usage in Mice with Diabetes-Associated Cognitive Decline

    Fibroblast growth factor 21 (FGF21) is an endocrine hormone that exerts beneficial effects on glucose and lipid metabolic homeostasis. However, the impact of FGF21 on type 1 diabetes–associated cognitive decli...

    Liangcai Zhao, Haowei Jiang, Jiaojiao **e, Danjie Shen in Molecular Neurobiology (2022)

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    Time-Dependent Lactate Production and Amino Acid Utilization in Cultured Astrocytes Under High Glucose Exposure

    Accumulating investigations have focused on the severity of central nervous system (CNS) complications in diabetic patients. The effects of the high glucose (HG) probably attribute to the metabolic disturbance...

    Dan Wang, Liangcai Zhao, Hong Zheng, Minjian Dong, Linlin Pan in Molecular Neurobiology (2018)

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    NMR-Based Metabolomics Reveal a Recovery from Metabolic Changes in the Striatum of 6-OHDA-Induced Rats Treated with Basic Fibroblast Growth Factor

    Basic fibroblast growth factor (bFGF) has a potential role in the treatment of Parkinson’s disease (PD) due to its neurotrophic effect on dopaminergic neurons. To address the metabolic mechanisms of bFGF admin...

    Hong Zheng, Liangcai Zhao, Huanhuan **a, Cuicui Xu, Dan Wang in Molecular Neurobiology (2016)