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  1. Article

    Open Access

    MicroRNA-26b suppresses the NF-κB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3

    Abnormal activation of the NF-κB pathway is closely related to tumorigenesis and chemoresistance. Therefore, microRNAs that possess the NF-κB inhibitory activity may provide novel targets for anti-cancer thera...

    Na Zhao, Ruizhi Wang, Liangji Zhou, Ying Zhu, Jiao Gong, Shi-Mei Zhuang in Molecular Cancer (2014)

  2. No Access

    Article

    Plasma density evolution in plasma opening switch obtained by a time-resolved sensitive He-Ne interferometer

    To understand the formation process of vacuum gap in coaxial microsecond conduction time plasma opening switch (POS), we have made measurements of the line-integrated plasma density during switch operation usi...

    Lin Chen, **g Ren, Fan Guo, LiangJi Zhou in Science China Physics, Mechanics and Astro… (2014)

  3. Article

    SPRY4 inhibits and sensitizes the primary KIT mutants in gastrointestinal stromal tumors (GISTs) to imatinib

    KIT is frequently mutated in gastrointestinal stromal tumors (GISTs), and the treatment of GISTs largely relies on targeting KIT currently. In this study, we aimed to investigate the role of sprouty RTK signal...

    Shu**g Li, Sien Zhao, Nianhai Liang, Shaoting Zhang, Liangying Zhang in Gastric Cancer (2023)

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    Article

    RAF1 facilitates KIT signaling and serves as a potential treatment target for gastrointestinal stromal tumor

    The aberrant activation of RAS/RAF/MEK/ERK signaling is important for KIT mutation-mediated tumorigenesis of gastrointestinal stromal tumor (GIST). In this study, we found that inhibition of RAF1 suppresses th...

    Liangying Zhang, Shaoting Zhang, Xu Cao, Jun Shi, Sien Zhao, **hai Tian in Oncogene (2024)