14 Result(s)
within
LiHong Zhang
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessEstablishment and validation of an artificial intelligence-based model for real-time detection and classification of colorectal adenoma
Colorectal cancer (CRC) prevention requires early detection and removal of adenomas. We aimed to develop a computational model for real-time detection and classification of colorectal adenoma. Computationally ...
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Article
Open AccessLinking deeply-sourced volatile emissions to plateau growth dynamics in southeastern Tibetan Plateau
The episodic growth of high-elevation orogenic plateaux is controlled by a series of geodynamic processes. However, determining the underlying mechanisms that drive plateau growth dynamics over geological hist...
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Article
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)—a new coronavirus that has led to a worldwide pandemic1—has a furin cleavage site (PRRAR) in its spike protein that is absent in other group-2B coronav...
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Article
Open AccessTargeted disruption of pi–pi stacking in Malaysian banana lectin reduces mitogenicity while preserving antiviral activity
Lectins, carbohydrate-binding proteins, have been regarded as potential antiviral agents, as some can bind glycans on viral surface glycoproteins and inactivate their functions. However, clinical development o...
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Article
Open AccessGene duplication drives genome expansion in a major lineage of Thaumarchaeota
Ammonia-oxidising archaea of the phylum Thaumarchaeota are important organisms in the nitrogen cycle, but the mechanisms driving their radiation into diverse ecosystems remain underexplored. Here, existing tha...
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Open AccessNovel Pt–Ni Bimetallic Catalysts Pt(Ni)–LaFeO3/SiO2 via Lattice Atomic-Confined Reduction for Highly Efficient Isobutane Dehydrogenation
In this study, a series of novel Pt–Ni bimetallic catalysts supported on LaFeO3/SiO2 with different amounts of Ni were prepared by the lattice atomic-confined reduction of LaFe1−x(Ni, Pt)xO3/SiO2 perovskite precu...
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Article
Preparation of CeO2-Modified Mg(Al)O-Supported Pt–Cu Alloy Catalysts Derived from Hydrotalcite-Like Precursors and Their Catalytic Behavior for Direct Dehydrogenation of Propane
A series of PtCuCeMgAl quintuple hydrotalcite-like compounds with different Ce contents were synthesized by one-pot method. After calcining and reduction, CeO2-modified Mg(Al)O-supported Pt–Cu alloy catalysts wer...
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Article
Open AccessHighly Dispersed Pt Species with Excellent Stability and Catalytic Performance by Reducing a Perovskite-Type Oxide Precursor for CO Oxidation
A new scheme for the preparation of highly dispersed precious metal catalysts is proposed in this work. Samples of LaCo1−xPtxO3/SiO2 (x = 0.03, 0.05, 0.07, 0.09, and 0.10) were prepared through a simple method of...
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Article
Open AccessFavipiravir (T-705) protects against Nipah virus infection in the hamster model
Nipah and Hendra viruses are recently emerged bat-borne paramyxoviruses (genus Henipavirus) causing severe encephalitis and respiratory disease in humans with fatality rates ranging from 40–75%. Despite the sever...
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Open AccessOne-step generation of mice carrying a conditional allele together with an HA-tag insertion for the delta opioid receptor
G protein-coupled receptors (GPCRs) are important modulators of many physiological functions and excellent drug targets for many diseases. However, to study the functions of endogenous GPCRs is still a challen...
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Article
Open AccessTesticular Dnmt3 expression and global DNA methylation are down-regulated by gonadotropin releasing hormones in the ricefield eel Monopterus albus
In vertebrates, DNA methyltransferase 3 (Dnmt3) homologues are responsible for de novo DNA methylation and play important roles in germ cell development. In the present study, four dnmt3 genes, dnmt3aa, dnmt3ab, ...
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Article
Open AccessElevated serum transaminase activities were associated with increased serum levels of iron regulatory hormone hepcidin and hyperferritinemia risk
Iron imbalance is a feature of liver damage. However, the biological correlation of serum hepcidin, a key regulator of iron homeostasis, with liver malfunction is undefined. To this end, we piloted the Chinese...
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Article
Open AccessAssociations of prepregnancy body mass index and gestational weight gain with pregnancy outcomes in nulliparous women delivering single live babies
The study was to assess the associations of prepregnancy body mass index (BMI) and gestational weight gain (GWG) with pregnancy outcomes. This was a retrospective analysis of 2973 nulliparous women who deliver...
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Article
Specific targeted killing of ErbB2 positive breast cancer by retro virus-mediated Immunocaspase-3 secreting T cells
In this study, Immunocaspase-3 gene was transfected into Jurkat T lymphocytes and the targeted proapoptotic protein Immunocaspase-3 was stably secreted. Its entry to ErbB2 positive SKBr3 breast carcinoma cell lin...
