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Article
TGF-β1 -promoted epithelial-to-mesenchymal transformation and cell adhesion contribute to TGF-β1 -enhanced cell migration in SMMC-7721 cells
Transforming growth factor-β1 (TGF-β1), a multi-function polypeptide, is a double-edged sword in cancer. For some tumor cells, TGF-β1 is a potent growth inhibitor and apoptosis inducer. More commonly, TGF-β1 l...
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Article
Open AccessWhole pelvic helical tomotherapy for locally advanced cervical cancer: technical implementation of IMRT with helical tomothearapy
To review the experience and to evaluate the treatment plan of using helical tomotherapy (HT) for the treatment of cervical cancer.
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Article
Open AccessToxicity risk of non-target organs at risk receiving low-dose radiation: case report
The spine is the most common site for bone metastases. Radiation therapy is a common treatment for palliation of pain and for prevention or treatment of spinal cord compression. Helical tomotherapy (HT), a new...
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Article
Open AccessAbdominal irradiation modulates 5-Fluorouracil pharmacokinetics
Concurrent chemoradiation with 5-fluorouracil (5-FU) is widely accepted for treatment of abdominal malignancy. Nonetheless, the interactions between radiation and 5-FU remain unclear. We evaluated the influenc...
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Article
Open AccessComparison of coplanar and noncoplanar intensity-modulated radiation therapy and helical tomotherapy for hepatocellular carcinoma
To compare the differences in dose-volume data among coplanar intensity modulated radiotherapy (IMRT), noncoplanar IMRT, and helical tomotherapy (HT) among patients with hepatocellular carcinoma (HCC) and port...
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Article
Open AccessShould helical tomotherapy replace brachytherapy for cervical cancer? Case report
Stereotactic body radiation therapy (SBRT) administered via a helical tomotherapy (HT) system is an effective modality for treating lung cancer and metastatic liver tumors. Whether SBRT delivered via HT is a f...
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Article
Open AccessToxic risk of stereotactic body radiotherapy and concurrent helical tomotherapy followed by erlotinib for non-small-cell lung cancer treatment - case report
Stereotactic body radiation therapy (SBRT) applied by helical tomotherapy (HT) is feasible for lung cancer in clinical. Using SBRT concurrently with erlotinib for non-small cell lung cancer (NSCLC) is not repo...
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Article
Open AccessImage-guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high-risk oral cavity cancer
The aim of this study was to assess the treatment results and toxicity profiles of helical tomotherapy (HT) for postoperative high-risk oral cavity cancer.
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Article
Open AccessIntensity modulated radiotherapy for elderly bladder cancer patients
To review our experience and evaluate treatment planning using intensity-modulated radiotherapy (IMRT) and helical tomotherapy (HT) for the treatment of elderly patients with bladder cancer.
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Article
Open AccessRelationship of carotid intima-media thickness and duration of vegetarian diet in Chinese male vegetarians
Many studies have shown that vegetarian diet has beneficial effects on the prevention of cardiovascular diseases. However, the effect of vegetarian diet on carotid intima-media thickness (IMT), as well as the ...
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Article
Open AccessHead and neck irradiation modulates pharmacokinetics of 5-fluorouracil and cisplatin
5-fluorouracil (5-FU) and cisplatin (CDDP) are used to enhance radiotherapy (RT) effect for head and neck (HN) cancers. However, the effect of local RT on systemic chemotherapeutics remains unclear. Here, we e...
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Article
Erratum to: Paenibacillus bei**gensis sp. nov., a nitrogen-fixing species isolated from wheat rhizosphere soil
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Article
Open AccessTime-dependent variation of pathways and networks in a 24-hour window after cerebral ischemia-reperfusion injury
Cerebral ischemia-reperfusion injury may simultaneously result in functional variation of multiple genes/pathways. However, most prior time-sequence studies on its pathomechanism only focused on a single gene ...
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Article
Open AccessLocal pelvic irradiation modulates Pharmacokinetics of 5-Fluorouracil in the plasma but not in the Lymphatic System
5-fluorouracil (5-FU) is employed to enhance radiotherapy (RT) effect. Here, we evaluated the influence of whole-pelvic irradiation on the pharmacokinetics (PK) of 5-FU in plasma and lymphatic system of rats a...
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Article
Open AccessAcetylation of MAT IIα represses tumour cell growth and is decreased in human hepatocellular cancer
Metabolic alteration is a hallmark of cancer. Dysregulation of methionine metabolism is implicated in human liver cancer. Methionine adenosyltransferase IIα (MAT IIα) is a key enzyme in the methionine cycle, c...
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Article
Open AccessAnaerolineaceae and Methanosaeta turned to be the dominant microorganisms in alkanes-dependent methanogenic culture after long-term of incubation
The methanogenic alkanes-degrading enrichment culture which had been incubated for over 1,300 days amended with n-alkanes (C15–C20) was investigated through clone libraries of bacteria, archaea and assA, mcrA fun...
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Article
Open AccessImpact of postoperative daily image-guided intensity-modulated radiotherapy on overall and local progression-free survival in patients with oral cavity cancer
We compared the outcome of patients who received non-image-guided intensity-modulated radiotherapy (IMRT) with those who received helical tomotherapy (HT), a daily image-guided radiotherapy (IGRT), after surge...
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Article
Open AccessGenome-wide transcriptome profiling of nitrogen fixation in Paenibacillus sp. WLY78
Diazotrophic (nitrogen-fixing) Gram-positive and endospore-formed Paenibacillus spp. have potential uses as a bacterial fertilizer in agriculture. The transcriptional analysis of nitrogen fixation in Paenibacillu...
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Article
Open AccessSpatial analysis of visceral leishmaniasis in the oases of the plains of Kashi Prefecture, **njiang Uygur Autonomous Region, China
Kashi Prefecture of **njiang is one of the most seriously affected areas with anthroponotic visceral leishmaniasis in China. A better understanding of space distribution features in this area was needed to gui...
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Article
Open AccessHelical unwinding and side-chain unlocking unravel the outward open conformation of the melibiose transporter
Molecular dynamics simulations have been used to study the alternate access mechanism of the melibiose transporter from Escherichia coli. Starting from the outward-facing partially occluded form, 2 out of 12 simu...
