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    Article

    Reduction of Benzaldehyde Catalyzed by Papain-Based Semisynthetic Enzymes

    Some features of native enzyme’s active site were used to conjunction with a chemical reagent or modifying group, which would generate new functionality different from the natural enzyme. In order to obtain an...

    Chun-xiang Chen, Bo Jiang, E. A. Carrey in Applied Biochemistry and Biotechnology (2010)

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    Multicomponent Amorphous Nanofibers Electrospun from Hot Aqueous Solutions of a Poorly Soluble Drug

    To design and fabricate multicomponent amorphous electrospun nanofibers for synergistically improving the dissolution rate and permeation profiles of poorly water-soluble drugs.

    Deng-Guang Yu, Li-Dong Gao, Kenneth White in Pharmaceutical Research (2010)

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    Article

    Kinetic Evaluation of Aminoethylisothiourea on Mushroom Tyrosinase Activity

    This study demonstrates that aminoethylisothiourea (AET), a potent inhibitor of inducible nitric oxide synthase, is an irreversible competitive inhibitor of mushroom tyrosinase by chelation to the active site ...

    Shu-Bai Li, Hua-Li Nie, Hai-Tao Zhang, Yong Xue in Applied Biochemistry and Biotechnology (2010)

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    Dissolution Improvement of Electrospun Nanofiber-Based Solid Dispersions for Acetaminophen

    The objective of the present investigation was to prepare novel solid dispersions (SDs) of poorly water-soluble drugs with special microstructural characteristics using electrospinning process. With the hydrop...

    Deng-Guang Yu, Christopher Branford-White, Kenneth White, Xue-Lian Li in AAPS PharmSciTech (2010)

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    In Vitro Effect of Ozagrel on Mushroom Tyrosinase

    This investigation, in vitro, shows that ozagrel, an antithrombotic drug, inhibited both monophenolase and diphenolase activities of mushroom tyrosinase when l-tyrosine and l-DOPA were assayed spectrophotometrica...

    Shu-Bai Li, Yong Xue, **n-Yu Lv, Hua-Li Nie, Li-Min Zhu in The Protein Journal (2009)

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    The purification and characterization of deoxycytidine kinase from calf thymus

    A facile and fast approach for the purification of deoxycytidine kinase (dCK) from calf thymus was developed using a fast performance liquid chromatography system. A 73-fold enrichment of the enzyme was noted ...

    **g Quan, Yan-Qian Chai in World Journal of Microbiology and Biotechn… (2009)

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    Lipase-catalyzed transesterification of soybean oil for biodiesel production in tert-amyl alcohol

    Lipase-catalyzed transesterification of soybean oil and methanol for biodiesel production in tert-amyl alcohol was investigated. The effects of different organic medium, molar ratio of substrate, reaction tempera...

    Yan Zheng, **g Quan, **n Ning, Li-Min Zhu in World Journal of Microbiology and Biotechn… (2009)

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    Enantioselective reductive amination of α-keto acids by papain-based semisynthetic enzyme

    Alkylation of a cysteine residue in papain with a pyridoxamine (PX) cofactor was carried out. The resulting semisynthetic enzyme (papain-PX) has no detectable protease activity but has the ability to catalyze ...

    Chun-**ang Chen, Bo Jiang, C. Branford-White, Li-Min Zhu in Biochemistry (Moscow) (2009)

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    Epoxypropane biosynthesis by Methylomonas sp. GYJ3: batch and continuous studies

    Methylomonas sp. GYJ3 is a methanotrophic bacterium containing methane monooxygenase (MMO), which catalyses the epoxidation of propene to epoxypropane. In this study, the cell suspension of Methylomonas sp. GYJ3...

    Jia-Ying **n, Jun-Ru Cui, Li-Min Zhu in World Journal of Microbiology and Biotechn… (2002)