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Angelica dahurica extract and its effective component bergapten alleviated hepatic fibrosis by activating FXR signaling pathway

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  1. Article

    Open Access

    The complete plastomes of thirteen Libanotis (Apiaceae, Apioideae) plants: comparative and phylogenetic analyses provide insights into the plastome evolution and taxonomy of Libanotis

    The genus Libanotis Haller ex Zinn, nom. cons., a contentious member of Apiaceae, encompasses numerous economically and medicinally significant plants, comprising approximately 30 species distributed across Euras...

    Li-Jia Liu, Chang-Kun Liu, **g Cai, Jiao-Jiao Deng, **ng‑** He in BMC Plant Biology (2024)

  2. Article

    Phytochemistry, data mining, pharmacology, toxicology and the analytical methods of Cyperus rotundus L. (Cyperaceae): a comprehensive review

    Cyperus rotundus L. has been widely used in the treatment and prevention of numerous diseases in traditional systems of medicine around the world, such as nervous, gastrointestinal systems diseases and inflammati...

    Bian-**a Xue, Ru-Shang He, Jia-**n Lai, Nana Ama Mireku-Gyimah in Phytochemistry Reviews (2023)

  3. Article

    Open Access

    Function and molecular mechanism analysis of CaLasSDE460 effector involved in the pathogenesis of “Candidatus Liberibacter asiaticus” in citrus

    Citrus Huanglongbing (HLB), caused by Candidatus Liberibacter asiaticus (CaLas), is the most serious disease worldwide. CaLasSDE460 was previously characterized as a potential virulence factor of CaLas. However, ...

    Shuai Wang, Meixia Du, Liting Dong, Rongrong Qu, Danlu Ran in Molecular Horticulture (2023)

  4. Article

    Open Access

    Uncarialines A-E, new alkaloids from Uncaria rhynchophylla and their anticoagulant activity

    Uncarialines A-E (1–5), five undescribed monoterpene indole alkaloids, together with five known analogues were obtained from the stems of Uncaria rhynchophylla. Alkaloids 13 were unique 3,4-seco-tricyclic alkalo...

    Ke-Pu Huang, Li-Li Xu, Sheng Li, Yin-Ling Wei in Natural Products and Bioprospecting (2023)

  5. Article

    Open Access

    Identification and Characterization of Bacillus subtilis B9: A Diazotrophic Plant Growth-Promoting Endophytic Bacterium Isolated from Sugarcane Root

    Plant endophytic microorganisms, which can enhance plant growth and resistance to biotic and abiotic stresses, are untapped resources with large potential applications for crop production. However, the endophy...

    Yi-ning Di, Ling Kui, Pratiksha Singh, Lu-feng Liu in Journal of Plant Growth Regulation (2023)

  6. Article

    Open Access

    3′ UTR is critical for viral RNA accumulation of jasmine virus H

    Jasmine virus H (JaVH) is a newly reported viral pathogen of jasmine in China and USA. To study the viral gene function and pathogenic mechanism, a full-length infectious clone of JaVH (pXT-JaVHFJ) was constructe...

    Li-Juan Zhu, Chong-Tao Zhang, Ya-Ni Bai, Chao-Yang Jiang in Phytopathology Research (2023)

  7. Article

    Open Access

    The PPR-Domain Protein SOAR1 Regulates Salt Tolerance in Rice

    Previous studies in Arabidopsis reported that the PPR protein SOAR1 plays critical roles in plant response to salt stress. In this study, we reported that expression of the Arabidopsis SOAR1 (AtSOAR1) in rice sig...

    Kai Lu, Cheng Li, Ju Guan, Wen-Hua Liang, Tao Chen, Qing-Yong Zhao, Zhen Zhu in Rice (2022)

  8. Article

    Open Access

    Scaling-up and proteomic analysis reveals photosynthetic and metabolic insights toward prolonged H2 photoproduction in Chlamydomonas hpm91 mutant lacking proton gradient regulation 5 (PGR5)

    Clean and sustainable H2 production is crucial to a carbon–neutral world. H2 generation by Chlamydomonas reinhardtii is an attractive approach for solar-H2 from H2O. However, it is currently not large-scalable be...

    Peng Liu, De-Min Ye, Mei Chen, ** Zhang, **a-He Huang in Photosynthesis Research (2022)

  9. Article

    Open Access

    Loss of glucosylceramide synthase impairs the growth and virulence of Fusarium oxysporum f. sp. cubense

    Glucosylceramides are a class of membrane lipids that serve as vital structural and signaling molecules in eukaryotes. In this study, we explored the function of FocGCS, a glucosylceramide synthase (GCS) in Fusar...

    Jian Wang, Kun Zhang, Li-Qun Huang, He-Nan Bao, Na Hai in Phytopathology Research (2022)

  10. Article

    Open Access

    Artemyrianosins A–J, cytotoxic germacrane-type sesquiterpene lactones from Artemisia myriantha

    Ten new germacrane-type sesquiterpenoids, artemyrianosins A–J (110), were isolated from the aerial parts of Artemisia myriantha. Their structures were elucidated by spectral analyses including UV, IR, HRESIMS, 1...

    **n Zhang, Yun-Bao Ma, **ao-Feng He, Tian-Ze Li in Natural Products and Bioprospecting (2022)

  11. Article

    Open Access

    Demethylzeylasteral (T-96) initiates extrinsic apoptosis against prostate cancer cells by inducing ROS-mediated ER stress and suppressing autophagic flux

    Demethylzeylasteral (T-96) is a pharmacologically active triterpenoid monomer extracted from Tripterygium wilfordii Hook F (TWHF) that has been reported to exhibit anti-neoplastic effects against several types of...

    Dong-lin Yang, Ya-jun Zhang, Liu-jun He, Chun-sheng Hu, Li-xia Gao in Biological Research (2021)

  12. Article

    Open Access

    Membrane lipid raft organization during cotton fiber development

    Cotton fiber is a single-celled seed trichome that originates from the ovule epidermis. It is an excellent model for studying cell elongation. Along with the elongation of cotton fiber cell, the plasma membran...

    Fan XU, **aodong SUO, Fang LI, Chaoya BAO, Shengyang HE in Journal of Cotton Research (2020)

  13. Article

    Open Access

    Whole-transcriptome RNA sequencing reveals the global molecular responses and ceRNA regulatory network of mRNAs, lncRNAs, miRNAs and circRNAs in response to copper toxicity in Ziyang **angcheng (Citrus junos Sieb. Ex Tanaka)

    Copper (Cu) toxicity has become a potential threat for citrus production, but little is known about related mechanisms. This study aims to uncover the global landscape of mRNAs, long non-coding RNAs (lncRNAs),...

    **ng-Zheng Fu, **ao-Yong Zhang, Jie-Ya Qiu, Xue Zhou, Meng Yuan in BMC Plant Biology (2019)

  14. Article

    Open Access

    Xylanilyticolides A–C, Three New Compounds from Cultures of the Actinomycete Promicromonospora xylanilytica YIM 61515

    Three new lactones, xylanilyticolides A–C (13), were isolated from cultures of the actinomycete Promicromonospora xylanilytica YIM 61515. Their structures were elucidated by 1D and 2D NMR spectroscopic data in c...

    Zhen-**ong Wang, Shen Qin, Li-Hua Xu, He-** Chen in Natural Products and Bioprospecting (2018)

  15. Article

    Open Access

    Pharmacokinetic Analysis of Four Bioactive Iridoid and Secoiridoid Glycoside Components of Radix Gentianae Macrophyllae and Their Synergistic Excretion by HPLC-DAD Combined with Second-Order Calibration

    An HPLC-DAD method combined with second-order calibration based on the alternating trilinear decomposition (ATLD) algorithm with the aid of region selection was developed to simultaneously and quantitatively c...

    Tian-Ming Yang, Yang-** Liu, Hai-Yan Fu, Wei Lan in Natural Products and Bioprospecting (2017)

  16. Article

    Open Access

    Mitochondrial pyruvate carrier 1 mediates abscisic acid-regulated stomatal closure and the drought response by affecting cellular pyruvate content in Arabidopsis thaliana

    Stomata are micropores surrounded by pairs of guard cells, and their opening is finely controlled to balance water vapor loss as transpiration and CO2 absorption for photosynthesis. The regulatory signaling netwo...

    Jian-Lin Shen, Chun-Long Li, Mei Wang, Li-Long He, Min-Yan Lin in BMC Plant Biology (2017)

  17. Article

    Open Access

    Functional analysis of Flavonoid 3′,5′-hydroxylase from Tea plant (Camellia sinensis): critical role in the accumulation of catechins

    Flavonoid 3′,5′-hydroxylase (F3′5′H), an important branch point enzyme in tea plant flavan-3-ol synthesis, belongs to the CYP75A subfamily and catalyzes the conversion of flavones, flavanones, dihydroflavonols...

    Yun-Sheng Wang, Yu-Jiao Xu, Li-** Gao, Oliver Yu, **n-Zhen Wang in BMC Plant Biology (2014)

  18. Article

    Open Access

    Carinatines A and B, Lycopodium Alkaloids from Phlegmariurus carinatus

    Carinatine A (1), a C16N2-type Lycopodium alkaloid possessing a 5/6/6/6 ring system formed by a new C-4/C-12 bond, and carinatine B (2), the first derivative of lycojaponicumin C, along 16 known compounds, were i...

    Fei Liu, Yu-Cheng Liu, Wei-Wei Jiang, Juan He in Natural Products and Bioprospecting (2014)

  19. Article

    Open Access

    Lycopodine-Type Alkaloids from Lycopodium japonicum

    Three new lycopodine-type alkaloids, 4α-hydroxyanhydrolycodoline (1), 4α,6α-dihydroxyanhydrolycodoline (2), and 6-epi-8β-acetoxylycoclavine (3), and an artifact, lycoposerramine G nitrate (4), along with seventee...

    Juan He, **ng-De Wu, Fei Liu, Yu-Cheng Liu in Natural Products and Bioprospecting (2014)

  20. Article

    Open Access

    Synthesis of l-Ascorbic Acid Lactone Derivatives

    A small focused library which comprised of l-AA lactone derivatives was built with a facile method. This reported method was optimized by modifying the acidity of the solvent. As a result, 12 l-AA lactones were s...

    Li-Dong Shao, Ya-Nan Wu, Jun Xu, Juan He, Yu Zhao in Natural Products and Bioprospecting (2014)

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