12 Result(s)
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Open AccessUncarialines A-E, new alkaloids from Uncaria rhynchophylla and their anticoagulant activity
Uncarialines A-E (1–5), five undescribed monoterpene indole alkaloids, together with five known analogues were obtained from the stems of Uncaria rhynchophylla. Alkaloids 1–3 were unique 3,4-seco-tricyclic alkalo...
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Open AccessArtemyrianosins A–J, cytotoxic germacrane-type sesquiterpene lactones from Artemisia myriantha
Ten new germacrane-type sesquiterpenoids, artemyrianosins A–J (1–10), were isolated from the aerial parts of Artemisia myriantha. Their structures were elucidated by spectral analyses including UV, IR, HRESIMS, 1...
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Open AccessXylanilyticolides A–C, Three New Compounds from Cultures of the Actinomycete Promicromonospora xylanilytica YIM 61515
Three new lactones, xylanilyticolides A–C (1–3), were isolated from cultures of the actinomycete Promicromonospora xylanilytica YIM 61515. Their structures were elucidated by 1D and 2D NMR spectroscopic data in c...
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Open AccessPharmacokinetic Analysis of Four Bioactive Iridoid and Secoiridoid Glycoside Components of Radix Gentianae Macrophyllae and Their Synergistic Excretion by HPLC-DAD Combined with Second-Order Calibration
An HPLC-DAD method combined with second-order calibration based on the alternating trilinear decomposition (ATLD) algorithm with the aid of region selection was developed to simultaneously and quantitatively c...
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Open AccessCarinatines A and B, Lycopodium Alkaloids from Phlegmariurus carinatus
Carinatine A (1), a C16N2-type Lycopodium alkaloid possessing a 5/6/6/6 ring system formed by a new C-4/C-12 bond, and carinatine B (2), the first derivative of lycojaponicumin C, along 16 known compounds, were i...
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Open AccessLycopodine-Type Alkaloids from Lycopodium japonicum
Three new lycopodine-type alkaloids, 4α-hydroxyanhydrolycodoline (1), 4α,6α-dihydroxyanhydrolycodoline (2), and 6-epi-8β-acetoxylycoclavine (3), and an artifact, lycoposerramine G nitrate (4), along with seventee...
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Open AccessSynthesis of l-Ascorbic Acid Lactone Derivatives
A small focused library which comprised of l-AA lactone derivatives was built with a facile method. This reported method was optimized by modifying the acidity of the solvent. As a result, 12 l-AA lactones were s...
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Open AccessFour new labdane-type diterpenoid glycosides from Diplopterygium laevissimum
Four new labdane-type diterpenoid glycosides, laevissiosides A-D (1–4) were isolated from the 95% ethanol extract of Diplopterygium laevissimum (Christ) Nakai, along with two known analogues, 18- β-D-glucopyranos...
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Open AccessNew Lycopodium alkaloids from Lycopodium obscurum
Three new Lycopodium alkaloids, obscurumines C-E (1–3), along with nine known compounds, were isolated from the club moss Lycopodium obscurum L. Structures of the new compounds were determined on the basis of the...
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Open AccessExploring of drug leads from diversity-oriented Michael-acceptor library derived from natural products
A potential strategy for drug lead identification and in-active natural products re-discovery is elaborated. Starting from fifteen structurally diverse natural products, a focused library featured by Michael a...
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Open AccessEuglobal-IIIa, a novel acylphloroglucinol-sesquiterpene derivative from Eucalyptus robusta: absolute structure and cytotoxicity
Euglobal-IIIa (1), a novel acylphloroglucinol-sesquiterpene derivative, and a known analogue, have been isolated from leaves of Eucalyptus robusta. The structures was elucidated by extensive spectroscopic data an...
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Open AccessChemical constituents from the aerial parts of Musella lasiocarpa
Phytochemical investigation of the aerial parts of the monotypic plant, Musella lasiocarpa, led to the isolation of four rare bicyclic diarylheptanoids, musellarins B-E (2–5), two new phenylphenalenones, 2-methox...
