1,069 Result(s)

Article

Moboa: a proposal for multiple objective bean optimization algorithm

The primary objective of multi-objective evolutionary algorithms (MOEAs) is to find a set of evenly distributed nondominated solutions that approximate the Pareto front (PF) of a multi-objective optimization p...

Lele **e, **aoli Lu, Hang Liu, Yongqiang Hu… in Complex & Intelligent Systems (2024)

Article

Analysis of the current status of "pseudo" unplanned endotracheal extubation in ICU patients in China's tertiary hospitals

To analyze the current status of "pseudo" unplanned endotracheal extubation in ICU patients in China's tertiary hospitals and to provide a reference for improving the quality of medical care. Through the Natio...

Qin Zhang, Li Wang, **aoli Liu, Zhenwei Liu, Zaichun Pu, Ziji Fang… in Scientific Reports (2024)

Article

Neoadjuvant camrelizumab (an anti-PD-1 antibody) plus chemotherapy or apatinib (a VEGFR-2 inhibitor) for initially unresectable stage II–III non-small-cell lung cancer: a multicentre, two-arm, phase 2 exploratory study

This multicentre, two-arm, phase 2 study aimed to explore the efficacy and safety of neoadjuvant camrelizumab plus chemotherapy or apatinib in patients with initially unresectable stage II–III non-small-cell l...

Haoran **a, Han Zhang, Zheng Ruan… in Signal Transduction and Targeted Therapy (2024)

Article

Correction: Human amnion mesenchymal stem cells promote endometrial repair via paracrine, preferentially than transdifferentiation

**yue Huang, **ao Yang, **glin Huang, Ling Wei… in Cell Communication and Signaling (2024)

Article

GD2 and its biosynthetic enzyme GD3 synthase promote tumorigenesis in prostate cancer by regulating cancer stem cell behavior

While better management of loco-regional prostate cancer (PC) has greatly improved survival, advanced PC remains a major cause of cancer deaths. Identification of novel targetable pathways that contribute to t...

Aaqib M. Bhat, Bhopal C. Mohapatra, Haitao Luan, Insha Mushtaq… in Scientific Reports (2024)

Article

A noise-robust voice conversion method with controllable background sounds

Background noises are usually treated as redundant or even harmful to voice conversion. Therefore, when converting noisy speech, a pretrained module of speech separation is usually deployed to estimate clean s...

Lele Chen, **ongwei Zhang, Yihao Li, Meng Sun, Weiwei Chen in Complex & Intelligent Systems (2024)

Article

Tumour microenvironment programming by an RNA–RNA-binding protein complex creates a druggable vulnerability in IDH-wild-type glioblastoma

Patients with IDH-wild-type glioblastomas have a poor five-year survival rate along with limited treatment efficacy due to immune cell (glioma-associated microglia and macrophages) infiltration promoting tumou...

Lele Wu, Zheng Zhao, Yong Jae Shin, Yiyun Yin, Anandhkumar Raju… in Nature Cell Biology (2024)

Article

Human amnion mesenchymal stem cells promote endometrial repair via paracrine, preferentially than transdifferentiation

Intrauterine adhesion (IUA) is one of the most severe causes of infertility in women of childbearing age with injured endometrium secondary to uterine performance. Stem cell therapy is effective in treating da...

**yue Huang, **ao Yang, **glin Huang, Ling Wei… in Cell Communication and Signaling (2024)

Article

Principal causes of water damage in mining roofs under giant thick topsoil–lilou coal mine

The roof water inrush disaster induced by coal mining is becoming a vital bottleneck restricting mine safety. To accurately predict the water inrush position of the coal seam roof sandstone aquifer and accurat...

Chao Niu, Qingfeng Tian, Lele **ao, **cheng Xue, Ruiqing Zhang… in Applied Water Science (2024)

Article

Malignant tumors in tuberous sclerosis complex: a case report and review of the literature

Tuberous sclerosis complex (TSC) is a rare, autosomal dominant genetic disease that arises from TSC1 or TSC2 genetic mutations. These genetic mutations can induce the development of benign tumors in any organ sys...

Cassie Liu, Subodh M. Lele, Martin H. Goodenberger… in BMC Medical Genomics (2024)

Article

Iron Metabolism and Ferroptosis in Early Brain Injury after Subarachnoid Haemorrhage

At present, it appears that the prognosis for subarachnoid haemorrhage (SAH), which has a high death and disability rate, cannot be greatly improved by medication or other treatment. Recent research suggests t...

Shihao Ge, Ziwen **g, Lele Wang, **aocong Cui, **n Zhang… in Molecular Neurobiology (2024)

Article

Research advances in the molecular classification of gastric cancer

Gastric cancer (GC) is a malignant tumor with one of the lowest five-year survival rates. Traditional first-line treatment regimens, such as platinum drugs, have limited therapeutic efficacy in treating advanc...

Dike Shi, Zihan Yang, Yanna Cai, Hongbo Li, Lele Lin, Dan Wu… in Cellular Oncology (2024)

Article

FGF21 attenuates neuroinflammation following subarachnoid hemorrhage through promoting mitophagy and inhibiting the cGAS-STING pathway

Subarachnoid hemorrhage (SAH) represents a form of cerebrovascular event characterized by a notable mortality and morbidity rate. Fibroblast growth factor 21 (FGF21), a versatile hormone predominantly synthesi...

Yue Ma, Zhiqin Liu, Lele Deng, **g**g Du… in Journal of Translational Medicine (2024)