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Article
Prevalence of oral HPV infection among healthy individuals and head and neck cancer cases in the French West Indies
Human papillomavirus (HPV) is known to play a role in the development of head and neck squamous cell carcinomas (HNSCC) and to date, no study has reported on the association between oral HPV infection and HNSC...
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Article
Open AccessLandfills and preterm birth in the Guadeloupe archipelago (French West Indies): a spatial cluster analysis
A high rate of preterm birth is observed in the Guadeloupe archipelago (French West Indies), raising the hypothesis of harmful environmental exposures, including landfilling. Our aim was to evaluate whether pr...
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Article
Prenatal and childhood exposure to chlordecone and sex-typed toy preference of 7-year-old Guadeloupean children
Chlordecone was used intensively as an insecticide in the French West Indies. Because of its high persistence, the resulting contamination of food and water has led to chronic exposure of the general populatio...
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Article
A cohort study of banana plantation workers in the French West Indies: first mortality analysis (2000–2015)
Chlordecone, an organochlorine insecticide, was widely used in the French West Indies banana plantations. We set up a cohort of banana plantation workers who worked between 1973 and 1993, the period of authori...
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Article
Open AccessHead and neck cancer risk factors in the French West Indies
The incidence of head and neck squamous cell carcinoma (HNSCC) in the French West Indies (FWI) is relatively high, despite a low prevalence of tobacco smoking and alcohol drinking. Little is known about other ...
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Article
Open AccessPrenatal and childhood exposure to chlordecone and adiposity of seven-year-old children in the Timoun mother–child cohort study in Guadeloupe (French West Indies)
Exposure to persistent environmental organic pollutants may contribute to the development of obesity among children. Chlordecone is a persistent organochlorine insecticide with estrogenic properties that was u...
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Article
Open AccessPrenatal and childhood chlordecone exposure, cognitive abilities and problem behaviors in 7-year-old children: the TIMOUN mother–child cohort in Guadeloupe
Chlordecone is a highly persistent organochlorine insecticide that was intensively used in banana fields in the French West Indies, resulting in a widespread contamination. Neurotoxicity of acute exposures in ...
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Article
Open AccessAssociation between sexual behaviour and head and neck cancer in the French West Indies: a case-control study based on an Afro-Caribbean population
Worldwide, a significant proportion of head and neck cancers is attributed to the Human papillomavirus (HPV). It is imperative that we acquire a solid understanding of the natural history of this virus in head...
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Article
Open AccessInverse association between plasma chlordecone concentrations and progression of alcoholic liver fibrosis: the role of liver metabolism
Chlordecone is a persistent organochlorinated insecticide, extensively used in the French West Indies and has been contaminating the population for more than thirty years. Its potentiation effect on hepatotoxi...