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Article
Open AccessMottling as a prognosis marker in cardiogenic shock
Impact of skin mottling has been poorly studied in patients admitted for cardiogenic shock. This study aimed to address this issue and identify determinants of 30-day and 1-year mortality in a large cardiogeni...
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Article
Uric acid levels are associated with endothelial dysfunction and severity of coronary atherosclerosis during a first episode of acute coronary syndrome
The role of serum uric acid in coronary artery disease has been extensively investigated. It was suggested that serum uric acid level (SUA) is an independent predictor of endothelial dysfunction and related to...
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Article
Controlled sedation with midazolam and analgesia with nalbuphine to alleviate pain in patients undergoing subcutaneous implantable cardioverter defibrillator implantation
Subcutaneous implantable cardioverter defibrillator (S-ICD) is an alternative to transvenous ICD to prevent sudden cardiac death. Subcutaneous ICD implantation frequently requires general anesthesia because of...
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Article
Open AccessSpare Adenosine A2a Receptors Are Associated with Positive Exercise Stress Test in Coronary Artery Disease
During exercise, cardiac oxygen consumption increases and the resulting low oxygen level in the myocardium triggers coronary vasodilation. This response to hypoxia is controlled notably by the vasodilator aden...
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Article
Clopidogrel Response Variability: Etiology and Clinical Relevance
Antiplatelet therapy is key to the care of coronary artery disease. Continuous improvement in the understanding of athero-thrombosis and the pathways of platelet activation has led to tremendous enhancement in...
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Article
Clinical Impact of Genetically Determined Platelet Reactivity
Dual antiplatelet therapy with aspirin and clopidogrel dramatically reduced the rate of major adverse cardiac events following percutaneous coronary intervention. Clopidogrel is a prodrug which requires a two-...
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Article
Genotypic and Phenotypic Assessment of Platelet Function and Response to P2Y12 Antagonists
The P2Y12-ADP receptor antagonists are the cornerstone of oral antiplatelet therapy in the secondary prevention of coronary artery disease, especially after acute coronary syndrome or percutaneous coronary int...
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Article
Personalized Antiplatelet Therapy: Review of the Latest Clinical Evidence
P2Y12-ADP receptor antagonist use has been critical in the development of percutaneous coronary intervention, dramatically reducing the rate of early stent thrombosis. However, it recently was observed that a ...
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Chapter
Actinomycose cardiaque
Homme de 54 ans, d’origine comorienne, présentant une fièvre dans un contexte d’altération de l’état général. La radiographie du thorax objective un foyer de pneumopathie supérieur droit. L’échographie cardiaq...