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  1. No Access

    Chapter

    Eicosapentaenoic Acid Alters Manganese Superoxide Dismutase Immunoreactive Protein Levels in Normal But not Maligant Central Nervous System Derived Cells

    The dose of radiation that safely can be administered to patients with malignant gliomas is limited by the potential for severe CNS morbidity. Manipulations that might increase the radiation sensitivity of gli...

    Geoffrey D. Girnun, Larry W. Oberley… in Eicosanoids and Other Bioactive Lipids in … (1999)

  2. No Access

    Article

    Inhibition of tumor cell growth by overexpression of manganese-containing superoxide dismutase

    Larry W. Oberley in AGE (1998)

  3. No Access

    Article

    Immunohistochemical localization of antioxidant enzymes during hamster kidney development

    Immunolocalization studies of hamster kidney development were performed using polyclonal antibodies to antioxidant enzymes, including antibodies to copper, zinc and manganese superoxide dismutases, catalase, g...

    Terry D. Oberley, Joan M. Sempf, Larry W. Oberley in The Histochemical Journal (1995)

  4. No Access

    Article

    Immunohistochemical localization of antioxidant enzymes during hamster kidney development

    Immunolocalization studies of hamster kidney development were performed using polyclonal antibodies to antioxidant enzymes, including antibodies to copper, zinc and manganese superoxide dismutases, catalase, g...

    Terry D. Oberley, Joan M. Sempf, Larry W. Oberley in The Histochemical Journal (1995)

  5. No Access

    Article

    Immunolocalization of antioxidant enzymes in adult hamster kidney

    Immunoperoxidase and immunogold techniques were used to localize the following antioxidant enzyme systems in the adult hamster kidney at the light and ultrastructural levels: superoxide dismutases, catalases, ...

    Kenneth E. Muse, Terry D. Oberley, Joan M. Sempf… in The Histochemical Journal (1994)

  6. No Access

    Article

    Immunolocalization of manganese superoxide dismutase in normal and transgenic mice expressing the human enzyme

    The localization of manganese superoxide dismutase (MnSOD) was determined using immunohistochemistry of various tissues of normal and transgenic mice which express the human enzyme, with emphasis on studies of...

    Terry D. Oberley, Douglas B. Coursin, Herbert P. Cihla… in The Histochemical Journal (1993)

  7. No Access

    Article

    Role of antioxidant enzymes in cell immortalization and transformation

    The role of antioxidant enzymes, particularly superoxide dismutase (SOD), in immortalization and malignant transformation is discussed. SOD (generally MnSOD) has been found to be lowered in a wide variety of t...

    Larry W. Oberley, Terry D. Oberley in Molecular and Cellular Biochemistry (1988)

  8. No Access

    Article

    In vitro modulation of antioxidant enzymes in normal and malignant renal epithelium

    The activities of three antioxidant enzymes, superoxide dismutase, catalase, and glutathione peroxidase, were monitored in isolated human renal adenocarcinoma tissues and in cultured human renal adenocarcinoma...

    An Hang Yang, Terry D. Oberley… in In Vitro Cellular & Developmental Biology (1987)

  9. No Access

    Article

    Kidney glomerular explants in serum-free media: Demonstration of intracellular antioxidant enzymes and active oxygen metabolites

    Guinea pig glomeruli were grown for 22 d in a serum-free medium composed of Waymouth's MB 752/1 supplemented with sodium pyruvate, nonessential amino acids, and antibiotics (the basic medium). Intracellular ce...

    Bruce W. Steinert, Paul J. Anderson… in In Vitro Cellular & Developmental Biology (1986)

  10. No Access

    Article

    Pharmacologic activities of copper compounds in chronic diseases

    Copper complexes have been shown to be effective antiinflammatory, antiulcer, anticonvulsant, anticancer, and antidiabetic agents. This seemingly diverse variety of pharmacologic effects is unified by the hypo...

    John R. J. Sorenson, Larry W. Oberley… in Biological Trace Element Research (1983)

  11. No Access

    Chapter

    Antitumor SOD Compounds

    Many studies have been recently performed on the activity of the enzyme superoxide dismutase (SOD) in tumor cells. This enzyme catalyzes the reaction ...

    Larry W. Oberley, Susan W. C. Leuthauser… in Inflammatory Diseases and Copper (1982)