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    Chapter

    Automation of Technology for Cancer Research

    Zebrafish embryos can be obtained for research purposes in large numbers at low cost and embryos develop externally in limited space, making them highly suitable for high-throughput cancer studies and drug scr...

    Wietske van der Ent, Wouter J. Veneman, Arwin Groenewoud in Cancer and Zebrafish (2016)

  2. Article

    Open Access

    miR-221-5p regulates proliferation and migration in human prostate cancer cells and reduces tumor growth in vivo

    Despite latest advances in prostate cancer (PCa) therapy, PCa remains the third-leading cause of cancer-related death in European men. Dysregulation of microRNAs (miRNAs), small non-coding RNA molecules with g...

    Mirjam Kiener, Lanpeng Chen, Markus Krebs, Joël Grosjean, Irena Klima in BMC Cancer (2019)

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    Article

    Bone marrow inflammation in haematological malignancies

    Tissue inflammation is a hallmark of tumour microenvironments. In the bone marrow, tumour-associated inflammation impacts normal niches for haematopoietic progenitor cells and mature immune cells and supports ...

    Madelon M. E. de Jong, Lanpeng Chen, Marc H. G. P. Raaijmakers in Nature Reviews Immunology (2024)