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    Article

    Inhibition of AXL enhances chemosensitivity of human ovarian cancer cells to cisplatin via decreasing glycolysis

    Anexelekto (AXL), a member of the TYRO3-AXL-MER (TAM) family of receptor tyrosine kinases (RTK), is overexpressed in varieties of tumor tissues and promotes tumor development by regulating cell proliferation, ...

    Min Tian, **-sha Chen, Lan-ya Li, Hai-zhou Wu, Da Zeng… in Acta Pharmacologica Sinica (2021)

  2. Article

    Anticancer strategies based on the metabolic profile of tumor cells: therapeutic targeting of the Warburg effect

    Tumor cells rely mainly on glycolysis for energy production even in the presence of sufficient oxygen, a phenomenon termed the Warburg effect, which is the most outstanding characteristic of energy metabolism ...

    **-sha Chen, Lan-ya Li, Yi-di Guan, **-ming Yang, Yan Cheng in Acta Pharmacologica Sinica (2016)

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