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  1. No Access

    Article

    Neuropilin-1 contributes to esophageal squamous cancer progression via promoting P65-dependent cell proliferation

    Neuropilin-1 (NRP1) is a non-kinase receptor recently implicated in tumor progression. Here we revealed that over-expression of NRP1 correlates with poor prognosis in esophageal squamous cell carcinoma (ESCC)....

    F Shi, L Shang, L-Y Yang, Y-Y Jiang, X-M Wang, J-J Hao, Y Zhang, D-K Huang… in Oncogene (2018)

  2. No Access

    Article

    Patient-reported outcome use in oncology: a systematic review of the impact on patient-clinician communication

    Patient-reported outcomes (PROs) are an increasingly popular tool to optimize care and bridge the gap between patient experience and clinician understanding. The aim of this review was to identify mechanisms t...

    L. Y. Yang, D. S. Manhas, A. F. Howard, R. A. Olson in Supportive Care in Cancer (2018)

  3. Article

    Open Access

    Expression of the TMPRSS2:ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer

    The prostate-specific gene, TMPRSS2 is fused with the gene for the transcription factor ERG in a large proportion of human prostate cancers. The prognostic significance of the presence of the TMPRSS2:ERG gene ...

    R K Nam, L Sugar, W Yang, S Srivastava, L H Klotz, L-Y Yang… in British Journal of Cancer (2007)

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  4. Article

    Open Access

    Genomic analysis reveals RhoC as a potential marker in hepatocellular carcinoma with poor prognosis

    Hepatocellular carcinoma (HCC) is one of the most malignant human tumours because of its high incidence of metastasis. The mechanisms underlying the metastasis of HCC, however, remain poorly understood. In thi...

    W Wang, L-Y Yang, G-W Huang, W-Q Lu, Z-L Yang, J-Q Yang… in British Journal of Cancer (2004)

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  5. No Access

    Article

    The activity of flavone acetic acid (NSC 347512) on human colon cancer cells in vitro

    Flavone acetic acid (FAA) was incubated for 1 to 48 hr with 3 established human colon cancer cell lines endowed with distinct degrees of phenotypic properties. All 3 lines responded to FAA in almost identical ...

    B. Drewinko M.D., Ph.D., L. -Y. Yang in Investigational New Drugs (1986)

  6. No Access

    Article

    The lethal activity and repair inhibition capacity of 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea

    The survival response of human colorectal carcinoma cells treated in vitro for 1 h with PCNU was characterized by a threshold exponential curve, Dq = 8 μg/ml (1 h) and D 0 = 22 ...

    B. Drewinko, L. -Y. Yang in Investigational New Drugs (1983)