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Article

IGFBP7 induces apoptosis of acute myeloid leukemia cells and synergizes with chemotherapy in suppression of leukemia cell survival

Despite high remission rates after chemotherapy, only 30–40% of acute myeloid leukemia (AML) patients survive 5 years after diagnosis. This extremely poor prognosis of AML is mainly caused by treatment failure...

H JMP Verhagen, D C de Leeuw, M GM Roemer, F Denkers, W Pouwels… in Cell Death & Disease (2014)