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Article
EBMT prospective observational study on allogeneic hematopoietic stem cell transplantation in T-prolymphocytic leukemia (T-PLL)
Preliminary data suggest that allogeneic stem cell transplantation (allo-SCT) may be effective in T-prolymphocytic leukemia (T-PLL). The purpose of the present observational study was to assess the outcome of ...
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Article
Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling
T-cell prolymphocytic leukemia (T-PLL) is a rare and aggressive neoplasm of mature T-cells with an urgent need for rationally designed therapies to address its notoriously chemo-refractory behavior. The median...
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Article
Erratum: GvL effects in T-prolymphocytic leukemia: evidence from MRD kinetics and TCR repertoire analyses
Correction to: Bone Marrow Transplantation (2017) 52, 544–551; doi:10.1038/bmt.2016.305; published online 12 December 2016 Since the online publication of this article the authors realised there were errors in...
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Article
GvL effects in T-prolymphocytic leukemia: evidence from MRD kinetics and TCR repertoire analyses
Allogeneic stem cell transplantation (alloSCT) is used for treating patients with T-prolymphocytic leukemia (T-PLL). However, direct evidence of GvL activity in T-PLL is lacking. We correlated minimal residual...
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Article
Dissection of CD20 regulation in lymphoma using RNAi
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Article
Thiotepa-based high-dose therapy for autologous stem cell transplantation in lymphoma: a retrospective study from the EBMT
Clinical information about thiotepa-based autologous stem cell transplantation (auto-SCT) outside the primary central nervous system lymphoma (PCNSL) field is sparse. In this registry-based retrospective study...
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Article
p53-dependent non-coding RNA networks in chronic lymphocytic leukemia
Mutations of the tumor suppressor p53 lead to chemotherapy resistance and a dismal prognosis in chronic lymphocytic leukemia (CLL). Whereas p53 targets are used to identify patient subgroups with impaired p53 ...
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Article
Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton
Chronic lymphocytic leukemia (CLL) is an incurable malignancy of mature B cells. One of the major challenges in treatment of CLL is the achievement of a complete remission to prevent relapse of disease origina...