25 Result(s)
within
L. M. Gershtein
Biomedicine
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Article
Morphochemical characteristics of neuron responses in functionally different brain structures to amphetamine treatment of different durations
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Article
Morphochemical characteristics of hippocampal neurons in rats with different behavioral parameters
The hippocampus (CA3 field) was studied in rats with different behavioral characteristics. Protein contents in the neuronal cytoplasm and nuclei, as well as the size of neurons in animals predisposed to stress...
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Morphochemical study of hippocampus of August rats after systemic treatment with amphetamine followed by injection of delta sleep-inducing peptide
Quantitative interferometry showed that chronic amphetamine administration to August rats (2.5 mg/kg/day for 3 weeks) increased the area of neuronal cytoplasm and nuclei and content and concentrations of prote...
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Article
Postresuscitation Changes in Neuronal Hippocampal Populations in Rats with Different Learning Ability
The state of pyramidal cell populations in CA1 and CA4 hippocampal fields was studied in resuscitated and intact rats with different learning ability. Morphometry showed that postresuscitation damage to neuron...
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Neurochemical characteristics of the effects of delta sleep-inducing peptide in wistar rats with hyperactivity of the dopaminergic system
Quantitative cytochemical assay showed that single injection of delta sleep-inducing peptide increased monoamine oxidase activity (substrates: serotonin and tryptamine) in the caudate and accumbens nuclei and ...
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Article
Neurochemical characteristics of the effects of delta sleep-inducing peptide in wistar rats with hyperactivity of the dopaminergic system
Quantitative cytochemical assay showed that single injection of delta sleep-inducing peptide increased monoamine oxidase activity (substrates: serotonin and tryptamine) in the caudate and accumbens nuclei and ...
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Article
Cytochemical characteristics of the brain in rats differing in active avoidance learning ability
Brain structures were examined in two mouse strains differing in active avoidance learning in a shuttle box. Protein content and concentration, area of the cytoplasm and nuclei of neuron in layers III and V of...
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Cytochemical characteristics of the brain in rats differing in active avoidance learning ability
Brain structures were examined in two mouse strains differing in active avoidance learning in a shuttle box. Protein content and concentration, area of the cytoplasm and nuclei of neuron in layers III and V of...
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Article
Morphochemical features of plastic rearrangements of hippocampal neurons after rhythmic stimulation of the limbs in elderly rabbits
The process of aging is accompanied by significant derangements to brain function, which are expressed particularly as the well-known phenomenon of memory disturbance [4, 5]. Since memory functions are based o...
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Article
Cytochemical parameters of synaptic neurons in rats with different abilities to learn a food-procuring habit
The characteristics of protein metabolism associated with cognitive activity were studied in neurons of layers III and IV of the sensorimotor cortex of rats, using two groups of Wistar rats. Regardless of the ...
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Article
Regulation by Delta-Sleep-Inducing Peptide of the Neurochemical Changes in the Brain Associated with Dopaminergic System Hyperactivity
The influence of a single injection of “delta-sleep-inducing peptide” (DSIP; 30 μg/kg body weight) on neurochemical parameters of rats' brain was studied under the conditions of chronic administration of dopam...
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Cytochemical characteristics of the brain of alcohol-nonpreferring wistar rats with different learning abilities
Quantitative cytochemical analysis of the activities of glucose-6-phosphate dehydrogenase, aminopeptidase, and glutamate dehydrogenase in the brain of Wistar rats with different learning abilities revealed a d...
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Protein content in rat brain neurons predisposed and resistant to emotional stress
Protein content was measured by interferometry in the cerebral neurons of August rats predisposed to emotional stress and Wistar rats resistant to it. Protein content was 16–18% lower in the neurons of the thi...
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Article
Morphochemical changes in brain structures in the course of chronic haloperidol treatment and the correction of these changes with tuftsin
The systemic injection of haloperidol (4 wk, 0.5 mg/kg/d) caused the increase of protein concentration and content, and the activity level of aminopeptidase in the cytoplasm of the neurons of associated type (...
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Article
Morphochemical features of sensorimotor cortex and neostriatum neurons in rats with different levels of alcohol preference
This paper reports interferometric studies of the contents and concentrations of proteins in the cellular structures of neurons of the sensorimotor cortex (layers III, V) and in the region of the caudate nucle...
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Morphochemical Changes in the Brain of Rats Under the Conditions of Dopamine System Dysfunction
Drugs regulating dopamine metabolism are widely used in the treatment of patients suffering from mental diseases whose pathogenesis is supposed to be connected with dopamine system dysfunction (1,3,4,8–10,13,1...
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Article
Morphochemical changes in brain structures and their correction by tuftsin in rats with hypofunction of the dopamine system
Chronic administration of haloperidol to Wistar rats induces specific changes in protein metabolism at the cortical-subcortical level (sensorimotor cortex—caudate nucleus), in associative and integrative trigg...
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Article
Some cytochemical peculiarities of the rat brain motor system after space flight
The results of cytochemical cytometry of rat brain suggest that a 9-day exposure of rats to microgravitation conditions lowers the activity of monoaminoxidase in the fibrous structures of layer V of the somato...
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Morphochemical manifestations of chronic exposure of the brain to amphetamine and their correction by delta-sleep peptide
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Article
Interhemispheric asymmetry of the nigrostriatal system in rats genetically predisposed to catalepsy
