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    A new PG13-based packaging cell line for stable production of clinical-grade self-inactivating γ-retroviral vectors using targeted integration

    The clinical application of self-inactivating (SIN) retroviral vectors has been hampered by the lack of reliable and efficient vector production technologies. To enable production of SIN γ-retroviral vectors f...

    R Loew, Y Meyer, K Kuehlcke, L Gama-Norton, D Wirth, H Hauser, S Stein… in Gene Therapy (2010)