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  1. No Access

    Article

    Urokinase-Type Plasminogen Activator Induces BV-2 Microglial Cell Migration Through Activation of Matrix Metalloproteinase-9

    In response to brain injury, microglia migrate and accumulate in the affected sites, which is an important step in the regulation of inflammation and neuronal degeneration/regeneration. In this study, we inves...

    Sun Mi Shin, Kyu Suk Cho, Min Sik Choi, Sung Hoon Lee… in Neurochemical Research (2010)

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    Article

    The Epigenetic Reader BRD2 as a Specific Modulator of PAI-1 Expression in Lipopolysaccharide-Stimulated Mouse Primary Astrocytes

    The post translational modification of lysine acetylation is a key mechanism that regulates chromatin structure. Epigenetic readers, such as the BET domains, are responsible for reading histone lysine acetylat...

    Chang Soon Choi, Seong Hwi Hong, Seobo Sim, Kyu Suk Cho… in Neurochemical Research (2015)

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    Article

    Proteinase 3 Induces Neuronal Cell Death Through Microglial Activation

    Proteinase 3 (PR3) is released from neutrophil granules and is involved in the inflammatory process. PR3 is implicated in antimicrobial defense and cell death, but the exact role of PR3 in the brain is less de...

    Kyu Suk Cho, Eun Joo Lee, Jung Nam Kim, Ji Woong Choi… in Neurochemical Research (2015)