390 Result(s)

Article

Limited impact of bacterial virulence on early mortality risk factors in Acinetobacter baumannii bacteremia observed in a Galleria mellonella model

Acinetobacter baumannii (AB) has emerged as a major pathogen in vulnerable and severely ill patients. It remains unclear whether early mortality (EM) due to AB bacteremia is because of worse clinical characterist...

Sin Young Ham, June Young Chun, Kyoung-Ho Song, Chang Kyung Kang… in Scientific Reports (2024)

Article

Clinical features of primary and compound forms of wide macular posterior staphyloma in high myopia

To compare the ocular features of highly myopic eyes with posterior staphyloma of wide macular type according to its morphological complexity.

Chang Ki Yoon, Eun Kyoung Lee, Kunho Bae, Un Chul Park in BMC Ophthalmology (2024)

Article

Diagnostic performance and image quality of an image-based denoising algorithm applied to radiation dose-reduced CT in diagnosing acute appendicitis

To evaluate diagnostic performance and image quality of ultralow-dose CT (ULDCT) in diagnosing acute appendicitis with an image-based deep-learning denoising algorithm (IDLDA).

Hyeon Ui Choi, Jungheum Cho, **hee Hwang, Seungjae Lee, Won Chang… in Abdominal Radiology (2024)

Article

scLENS: data-driven signal detection for unbiased scRNA-seq data analysis

High dimensionality and noise have limited the new biological insights that can be discovered in scRNA-seq data. While dimensionality reduction tools have been developed to extract biological signals from the ...

Hyun Kim, Won Chang, Seok Joo Chae, Jong-Eun Park, Minseok Seo… in Nature Communications (2024)

Article

Additive roles of antiferromagnetically coupled elements in the magnetic proximity effect in the GdFeCo/Pt system

Interfacial magnetic interactions between different elements are the origin of various spin-transport phenomena in multi-elemental magnetic systems. We investigate the coupling between the magnetic moments of ...

Jung Yun Kee, Kook Tae Kim, In Hak Lee, Ilwan Seo, Jun-Young Chang… in Scientific Reports (2024)

Article

The roles of health literacy and social support in the association between smartphone ownership and frailty in older adults: a moderated mediation model

Understanding the role of smartphones to promote the health status of older adults is important in the digital society. Little is known about the effects of having smartphones on physical frailty despite its p...

**seon Yi, Ju Young Yoon, Chang Won Won, Miji Kim, Kyoung Suk Lee in BMC Public Health (2024)

Article

The secreted protein Amuc_1409 from Akkermansia muciniphila improves gut health through intestinal stem cell regulation

Akkermansia muciniphila has received great attention because of its beneficial roles in gut health by regulating gut immunity, promoting intestinal epithelial development, and improving barrier integrity. However...

Eun-Jung Kang, Jae-Hoon Kim, Young Eun Kim, Hana Lee… in Nature Communications (2024)

Article

Sex-dependent different clinicopathological characterization of Epstein–Barr virus-associated gastric carcinoma: a large-scale study

Epstein–Barr virus (EBV)-associated gastric cancer (EBVaGC) has been reported to account for approximately 5–16% of all GCs with good prognosis compared to EBV-negative GC. We evaluated the clinicopathological...

Ji-Hyun Kim, Nayoung Kim, Du Hyun Song, Yonghoon Choi, Eun-Bi Jeon… in Gastric Cancer (2024)

Article

Integrative analysis of spatial and single-cell transcriptome data from human pancreatic cancer reveals an intermediate cancer cell population associated with poor prognosis

Recent studies using single-cell transcriptomic analysis have reported several distinct clusters of neoplastic epithelial cells and cancer-associated fibroblasts in the pancreatic cancer tumor microenvironment...

Seongryong Kim, Galam Leem, Junjeong Choi, Yongjun Koh, Suho Lee… in Genome Medicine (2024)

Article

Understanding the molecular mechanism of pathogenic variants of BIR2 domain in XIAP-deficient inflammatory bowel disease

X-linked inhibitor of apoptosis protein (XIAP) deficiency causes refractory inflammatory bowel disease. The XIAP protein plays a pivotal role in the pro-inflammatory response through the nucleotide-binding oli...

Juhwan Lee, Kyoung Mi Sim, Mooseok Kang, Hyun Ju Oh, Ho Jung Choi… in Scientific Reports (2024)

Article

Evaluation of an eight marker-panel including long mononucleotide repeat markers to detect microsatellite instability in colorectal, gastric, and endometrial cancers

Accurate determination of microsatellite instability (MSI) status is critical for optimal treatment in cancer patients. Conventional MSI markers can sometimes display subtle shifts that are difficult to interp...

Yousun Chung, Soo Kyung Nam, Ho Eun Chang, Cheol Lee, Gyeong Hoon Kang… in BMC Cancer (2023)

Article

Comparing zero-profile and conventional cage and plate in anterior cervical discectomy and fusion using finite-element modeling

Conventional cage and plate (CCP) implants usually used in ACDF surgery, do have limitations such as the development of postoperative dysphagia, adjacent segment degeneration, and soft tissue injury. To reduce...

Chang-Hwan Ahn, Sungwook Kang, Mingoo Cho, Seong-Hun Kim… in Scientific Reports (2023)

Article

Hepatic T-cell senescence and exhaustion are implicated in the progression of fatty liver disease in patients with type 2 diabetes and mouse model with nonalcoholic steatohepatitis

Immunosenescence and exhaustion are involved in the development and progression of type 2 diabetes (T2D) and metabolic liver diseases, including fatty liver, fibrosis, and cirrhosis, in humans. However, the re...

Byeong Chang Sim, Yea Eun Kang, Sun Kyoung You, Seong Eun Lee… in Cell Death & Disease (2023)

Article

Correction: Effect of Helicobacter pylori eradication after subtotal gastrectomy on the survival rate of patients with gastric cancer: follow-up for up to 15 years

Yonghoon Choi, Nayoung Kim, Chang Yong Yun, Yoon ** Choi, Hyuk Yoon… in Gastric Cancer (2023)