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Article
Understanding the Molecular Regulation of Serotonin Receptor 5-HTR1B-β-Arrestin1 Complex in Stress and Anxiety Disorders
The serotonin receptor subtype 5-HTR1B is widely distributed in the brain with an important role in various behavioral implications including neurological conditions and psychiatric disorders. The neuromodulatory...
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Article
Exploring the pharmacological aspects of natural phytochemicals against SARS-CoV-2 Nsp14 through an in silico approach
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), possesses an important bifunctional nonstructural protein (nsp14) with a C-terminal N7-methyltransferase (N7-MTase) domain and an N-terminal do...
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Chapter
Elucidating the Role of miRNA in Inflammasome-Mediated Immune Response in Leishmaniasis
The inflammasome is a cell cytoplasm-localized multimeric protein complex of host defense mechanism which gets activated due to infection in the innate immune system via pathogens or due to receiving cell dama...
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Article
Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors
Class B G-protein-coupled receptors (GPCRs) are receptors for peptide hormones that include glucagon, parathyroid hormone, and calcitonin. These receptors are involved in a wide spectrum of physiological activ...