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    Article

    Understanding the Molecular Regulation of Serotonin Receptor 5-HTR1B-β-Arrestin1 Complex in Stress and Anxiety Disorders

    The serotonin receptor subtype 5-HTR1B is widely distributed in the brain with an important role in various behavioral implications including neurological conditions and psychiatric disorders. The neuromodulatory...

    Oindrilla Dutta Gupta, Izhar Karbat, Kuntal Pal in Journal of Molecular Neuroscience (2023)

  2. Article

    Exploring the pharmacological aspects of natural phytochemicals against SARS-CoV-2 Nsp14 through an in silico approach

    The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), possesses an important bifunctional nonstructural protein (nsp14) with a C-terminal N7-methyltransferase (N7-MTase) domain and an N-terminal do...

    Arkajit De, Somdatta Bhattacharya, Bishal Debroy in In Silico Pharmacology (2023)

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    Elucidating the Role of miRNA in Inflammasome-Mediated Immune Response in Leishmaniasis

    The inflammasome is a cell cytoplasm-localized multimeric protein complex of host defense mechanism which gets activated due to infection in the innate immune system via pathogens or due to receiving cell dama...

    Ria Bhar, Kuntal Pal, Srijan Haldar in Pathobiology of Parasitic Protozoa: Dynami… (2023)

  4. Article

    Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors

    Class B G-protein-coupled receptors (GPCRs) are receptors for peptide hormones that include glucagon, parathyroid hormone, and calcitonin. These receptors are involved in a wide spectrum of physiological activ...

    Kuntal Pal, Karsten Melcher, H Eric Xu in Acta Pharmacologica Sinica (2012)