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  1. Article

    Risk of Hepatitis B Virus Reactivation in Rheumatoid Arthritis Patients Undergoing Tocilizumab-Containing Treatment

    To investigate the risk of hepatitis B virus reactivation in patients undergoing long-term tocilizumab therapy for rheumatoid arthritis.

    Meng Hsuan Kuo, Chih-Wei Tseng, Ming-Chi Lu in Digestive Diseases and Sciences (2021)

  2. No Access

    Article

    Risk factors, including different biologics, associated with depression and anxiety in patients with rheumatoid arthritis: a cross-sectional observational study

    To evaluate the associated factors of depression and anxiety in patients with rheumatoid arthritis (RA) and examine the effect of different biologics.

    Khai-**g Ng, Kuang-Yung Huang, Chien-Hsueh Tung, Bao-Bao Hsu in Clinical Rheumatology (2020)

  3. Article

    Open Access

    Increased peptidylarginine deiminases expression during the macrophage differentiation and participated inflammatory responses

    To investigate the expression of peptidylarginine deiminases (PADIs) during macrophage differentiation and its role in inflammatory responses.

    Ning-Sheng Lai, Hui-Chun Yu, Chien-Hsueh Tung in Arthritis Research & Therapy (2019)

  4. Article

    Open Access

    Aberrant expression of interleukin-23-regulated miRNAs in T cells from patients with ankylosing spondylitis

    Interleukin (IL)-23 can facilitate the differentiation of IL-17-producing helper T cells (Th17). The IL-23/IL-17 axis is known to play a key role in the immunopathogenesis of ankylosing spondylitis (AS). We hy...

    Ning-Sheng Lai, Hui-Chun Yu, Chien-Hsueh Tung in Arthritis Research & Therapy (2018)

  5. No Access

    Article

    Risks of hepatocellular carcinoma and cirrhosis-associated complications in patients with rheumatoid arthritis: a 10-year population-based cohort study in Taiwan

    Although rheumatoid arthritis (RA) has been linked to several important malignancies, data for the risks of hepatocellular carcinoma (HCC) in patients with RA are scarce. We aimed to examine the risk of HCC an...

    Ching-Sheng Hsu, Hui-Chu Lang, Kuang-Yung Huang, You-Chen Chao in Hepatology International (2018)

  6. Article

    Open Access

    The role of aberrant expression of T cell miRNAs affected by TNF-α in the immunopathogenesis of rheumatoid arthritis

    Tumor necrosis factor-alpha (TNF-α) can cause diverse T cell dysfunctions in patients with rheumatoid arthritis (RA). It is involved in the regulation of microRNAs (miRNAs) expression in different cell types. ...

    Ning-Sheng Lai, Hui-Chun Yu, Chien-Hsueh Tung in Arthritis Research & Therapy (2017)

  7. No Access

    Article

    Higher LPS-stimulated TNF-α mRNA levels in peripheral blood mononuclear cells from Chinese ankylosing spondylitis patients with −308G/A polymorphism in promoter region of tumor necrosis factor: association with distinct A33/B58/Cw10 haplotypes

    To investigate the effects of TNF-α −308, −238 promoter polymorphisms on TNF-α transcription in B27 positive Chinese patients with ankylosing spondylitis (AS). The possible relationship between polymorphisms, ...

    Ming-Chi Lu, K. L. Yang, Chien-Hsueh Tung, Kuang-Yung Huang in Rheumatology International (2008)