70 Result(s)
within
Kuan Teh JEANG
English
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Article
Open AccessRing finger protein 39 genetic variants associate with HIV-1 plasma viral loads and its replication in cell culture
The human immunodeficiency virus (HIV-1) exploits host proteins to complete its life cycle. Genome-wide siRNA approaches suggested that host proteins affect HIV-1 replication. However, the results barely overl...
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Open AccessA novel HSP90 inhibitor, 17-DMAG, induces Tax down-regulation and its oral administration to ATL-model mice intervenes against the infiltration property of the ATL-like lymphocytes and provides extended survival period
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Open AccessSorting nexin 24 genetic variation associates with coronary artery aneurysm severity in Kawasaki disease patients
The sorting nexin (SNX) family is involved in endocytosis and protein trafficking and plays multiple roles in various diseases. The role of SNX proteins in Kawasaki disease (KD) is not known. We attempted to t...
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Open AccessReviewer acknowledgement 2012
Retrovirology would like to thank the following for their assistance with peer review of manuscripts for the journal in 2012.
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Open AccessWip1 and p53 contribute to HTLV-1 Tax-induced tumorigenesis
Human T-cell Leukemia Virus type 1 (HTLV-1) infects 20 million individuals world-wide and causes Adult T-cell Leukemia/Lymphoma (ATLL), a highly aggressive T-cell cancer. ATLL is refractory to treatment with c...
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Open AccessHost restriction factors in retroviral infection: promises in virus-host interaction
Retroviruses have an intricate life cycle. There is much to be learned from studying retrovirus-host interactions. Among retroviruses, the primate lentiviruses have one of the more complex genome structures wi...
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Open AccessDiversity matters in scientific publishing
The importance of geographic diversity in publishing is emphasized in this editorial.
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Open AccessThe importance of ubiquitination and sumoylation on the transforming activity of HTLV Tax-1 and Tax-2
Human T-cell Leukemia Virus type 1 (HTLV-1) and 2 (HTLV-2) are two closely related human retroviruses. HTLV-1 is associated with an aggressive Adult T-cell Leukemia (ATL) while there is no evidence for an asso...
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Open AccessTombusvirus P19 RNA silencing suppressor (RSS) activity in mammalian cells correlates with charged amino acids that contribute to direct RNA-binding
Tombusvirus P19 is a protein encoded by tomato bushy stunt virus and related tombusviruses. Earlier studies have demonstrated that P19 is an RNA silencing suppressor (RSS) in plant cells. However, it has not b...
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Open AccessHighlights, predictions, and changes
Recent literature highlights at Retrovirology are described. Predictions are made regarding “hot” retrovirology research trends for the coming year based on recent journal access statistics. Changes in Retrovirol...
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Open AccessImpact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses
Autophagy is a protein degradative process important for normal cellular metabolism. It is apparently used also by cells to eliminate invading pathogens. Interestingly, many pathogens have learned to subvert t...
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Open AccessA measure of success
Cell and Bioscience is on track to receive its first Impact Factor in mid-2013. What is the role of the Impact Factor as a measure of a journal’s success?
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Open AccessOpen access, moving to the fore
Nine years after its founding, Retrovirology has moved to the forefront of virology journals in Impact Factor.
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Open AccessRNAi in the regulation of mammalian viral infections
Although RNA interference (RNAi) is known to play an important part in defense against viruses of invertebrates, its contribution to mammalian anti-viral defense has been a matter of dispute. This is surprisin...
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Open AccessUnstabilized DNA breaks in HTLV-1 Tax expressing cells correlate with functional targeting of Ku80, not PKcs, XRCC4, or H2AX
Expression of the human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein rapidily induces a significant increase of micronuclei (MN) and unstabilized DNA breaks in cells. Unstabilized DNA breaks can have ...
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Open AccessEpidermal growth factor receptor (EGFR) biology and Wnt developmental signaling highlight research endeavors of SCBA award winners
This months Cell and Bioscience highlights review articles by Mien-Chie Hung on EGFR biology and Yingzi Yang on Wnt signaling. Dr. Hung was the 2011 Society of Chinese Bioscientists in America (SCBA) Presidential...
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Open AccessThe 2011 Retrovirology Prize winner Masao Matsuoka: forward looking and antisense
Masao Matsuoka wins the 2011 Retrovirology Prize.
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Open AccessReplication competent HIV-1 viruses that express intragenomic microRNA reveal discrete RNA-interference mechanisms that affect viral replication
It remains unclear whether retroviruses can encode and express an intragenomic microRNA (miRNA). Some have suggested that processing by the Drosha and Dicer enzymes might preclude the viability of a replicatin...
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Open AccessEqual versus equivalent access to the scientific literature
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Open AccessRole of cellular factors in the replication of human retroviruses: recent insights
