10 Result(s)
within
Koji Tanaka
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessOne-year outcomes and safety assessment of faricimab in treatment-naïve patients with neovascular age-related macular degeneration in Japan
This multicentre retrospective study evaluated the 1-year outcomes and safety profile of faricimab in treatment-naïve patients with neovascular age-related macular degeneration (nAMD). Fifty-five patients (57 ...
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Article
Open AccessInfluence of ultrasound transmit frequency on measurement of global longitudinal strain on 2D speckle tracking echocardiography
The reproducibility of longitudinal strain measured by 2D speckle tracking echocardiography (2DSTE) may be affected by ultrasound settings. This study investigated the effect of transmit ultrasound frequency o...
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Article
Open AccessThree-month outcomes of faricimab loading therapy for wet age-related macular degeneration in Japan
This multicenter study aimed to assess the short-term effectiveness and safety of faricimab in treatment-naïve patients with wet age-related macular degeneration (wAMD) in Japan. We retrospectively reviewed 63...
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Article
Open AccessIncidence and risk of advanced age-related macular degeneration in eyes with drusenoid pigment epithelial detachment
To investigate the incidence and risk of advanced age-related macular degeneration (AMD), including geographic atrophy (GA) and macular neovascularization (MNV), in eyes with drusenoid pigment epithelial detac...
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Article
Open AccessAnti-metastatic effect of methylprednisolone targeting vascular endothelial cells under surgical stress
Perioperative systemic inflammation induced by surgical stress elevates the risk of hematogenous cancer metastasis. This study investigated the anti-metastatic effects and mechanisms of methylprednisolone (MP)...
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Article
Open AccessThe endoluminal pressures during flexible gastrointestinal endoscopy
In flexible gastrointestinal (GI) endoscopy, endoscopic insufflation is crucial and directly affects visualization. Optimal visualization enables endoscopists to conduct better examinations and administer opti...
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Article
Open AccessCentral serous chorioretinopathy and heart rate variability analysis with a smartphone application
The purpose of this study was to quantitatively analyze heart rate variability (HRV) in patients with central serous chorioretinopathy (CSC) by using a smartphone-based application (ANBAI: DUMSCO Inc.) for mea...
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Open AccessInterplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma
Notch1 transactivates Notch3 to drive terminal differentiation in stratified squamous epithelia. Notch1 and other Notch receptor paralogs cooperate to act as a tumor suppressor in squamous cell carcinomas (SCCs)....
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Article
Open AccessFish oil-enriched nutrition combined with systemic chemotherapy for gastrointestinal cancer patients with cancer cachexia
Despite recent advances in chemotherapy for gastrointestinal cancer, a crucial factor related to poor prognosis is reduced tolerance to chemotherapy induced by cancer cachexia. Fish oil (FO)-derived eicosapent...
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Article
Open AccessStructural basis for self-assembly of a cytolytic pore lined by protein and lipid
Pore-forming toxins (PFT) are water-soluble proteins that possess the remarkable ability to self-assemble on the membrane of target cells, where they form pores causing cell damage. Here, we elucidate the mech...
