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  1. No Access

    Article

    Malaria is a cause of iron deficiency in African children

    Malaria and iron deficiency (ID) are common and interrelated public health problems in African children. Observational data suggest that interrupting malaria transmission reduces the prevalence of ID1. To test th...

    John Muthii Muriuki, Alexander J. Mentzer, Ruth Mitchell, Emily L. Webb… in Nature Medicine (2021)

  2. No Access

    Article

    Genomic analysis of local variation and recent evolution in Plasmodium vivax

    Dominic Kwiatkowski and colleagues report a population genomic analysis of 228 clinical samples of Plasmodium vivax from 13 countries, with an emphasis on Southeast Asia. They analyze patterns of genetic structur...

    Richard D Pearson, Roberto Amato, Sarah Auburn, Olivo Miotto… in Nature Genetics (2016)

  3. No Access

    Article

    Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

    Dominic Kwiatkowski and colleagues report analysis of genetic variation in 826 Plasmodium falciparum samples collected from 10 locations in West Africa and southeast Asia. They characterize the population structu...

    Olivo Miotto, Jacob Almagro-Garcia, Magnus Manske, Bronwyn MacInnis… in Nature Genetics (2013)

  4. Article

    Genome-wide and fine-resolution association analysis of malaria in West Africa

    Dominic Kwiatkowski and colleagues of the MalariaGEN and the WTCCC consortiums report a genome-wide analysis of severe malaria in The Gambia. They provide guidance for design of GWAS in African populations, an...

    Muminatou Jallow, Yik Ying Teo, Kerrin S Small, Kirk A Rockett… in Nature Genetics (2009)

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  5. No Access

    Article

    In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading

    In vivo characterization of regulatory polymorphisms is a key requirement for next-generation human genetic analysis. Here we describe haploChIP, a method that uses chromatin immunoprecipitation (ChIP) and mass s...

    Julian C. Knight, Brendan J. Keating, Kirk A. Rockett… in Nature Genetics (2003)

  6. No Access

    Article

    Variable major lipoprotein is a principal TNF-inducing factor of louse-borne relapsing fever

    Massive release of tumor necrosis factor is responsible for the potentially fatal Jarisch-Herxheimer reaction that follows antibiotic treatment of relapsing fever due to Borrelia...

    Vincent Vidal, Ian G. Scragg, Sally J. Cutler, Kirk A. Rockett… in Nature Medicine (1998)