6 Result(s)
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Article
Open AccessNasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD
Nasal saline irrigation is highly recommended in patients following functional endoscopic sinus surgery (FESS) to aid the postoperative recovery. Post-FESS patients have significantly altered anatomy leading t...
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Article
Open AccessComparison of Sinus Deposition from an Aqueous Nasal Spray and Pressurised MDI in a Post-Endoscopic Sinus Surgery Nasal Replica
Optimising intranasal distribution and retention of topical therapy is essential for effectively managing patients with chronic rhinosinusitis, including those that have had functional endoscopic sinus surgery...
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Article
Open AccessCorrelation of regional deposition dosage for inhaled nanoparticles in human and rat olfactory
Nose-to-brain transport of airborne ultrafine particles (UFPs) via the olfactory pathway has been verified as a possible route for particle translocation into the brain. The exact relationship between increase...
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Article
Numerical Comparison of Nasal Aerosol Administration Systems for Efficient Nose-to-Brain Drug Delivery
Nose-to-brain drug administration along the olfactory and trigeminal nerve pathways offers an alternative route for the treatment of central nervous system (CNS) disorders. The characterization of particle dep...
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Article
Open AccessA combined experimental and numerical study on upper airway dosimetry of inhaled nanoparticles from an electrical discharge machine shop
Exposure to nanoparticles in the workplace is a health concern to occupational workers with increased risk of develo** respiratory, cardiovascular, and neurological disorders. Based on animal inhalation stud...
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Article
High Resolution Visualization and Analysis of Nasal Spray Drug Delivery
Effective nasal drug delivery of new-generation systemic drugs requires efficient devices that can achieve targeted drug delivery. It has been established that droplet size, spray plume, and droplet velocity a...
