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Article
An efficient multi-path structure with staged connection and multi-scale mechanism for text-to-image synthesis
Generating a realistic image which matches the given text description is a challenging task. The multi-stage framework obtains the high-resolution image by constructing a low-resolution image firstly, which is...
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Article
Open AccessNetAct: a computational platform to construct core transcription factor regulatory networks using gene activity
A major question in systems biology is how to identify the core gene regulatory circuit that governs the decision-making of a biological process. Here, we develop a computational platform, named NetAct, for co...
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Article
A multi-use deep learning method for CITE-seq and single-cell RNA-seq data integration with cell surface protein prediction and imputation
CITE-seq, a single-cell multi-omics technology that measures RNA and protein expression simultaneously in single cells, has been widely applied in biomedical research, especially in immune-related disorders an...
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Article
Open AccessEvaluation of some aspects in supervised cell type identification for single-cell RNA-seq: classifier, feature selection, and reference construction
Cell type identification is one of the most important questions in single-cell RNA sequencing (scRNA-seq) data analysis. With the accumulation of public scRNA-seq data, supervised cell type identification meth...
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Article
Consolidation of Pure Magnesium Powder by Equal-Channel Angular Pressing with Back Pressure
Pure Mg particles were consolidated by equal-channel angular pressing (ECAP) with back pressure at 423 K. Fully dense bulk Mg with a homogeneous grain structure was obtained. After multiple passes, grains were...
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Article
Open AccessPhased diploid genome assemblies and pan-genomes provide insights into the genetic history of apple domestication
Domestication of the apple was mainly driven by interspecific hybridization. In the present study, we report the haplotype-resolved genomes of the cultivated apple (Malus domestica cv. Gala) and its two major wil...
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Article
High strength biocomposites consolidated from hardwood particles by severe plastic deformation
Biocomposites were produced by equal channel angular pressing (ECAP) of wood particles with addition of polyethylenimine (PEI) to improve processability and binding performance. The highest flexural strength o...
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Article
Open AccessGenome re-sequencing reveals the history of apple and supports a two-stage model for fruit enlargement
Human selection has reshaped crop genomes. Here we report an apple genome variation map generated through genome sequencing of 117 diverse accessions. A comprehensive model of apple speciation and domesticatio...
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Article
Achieving Fine Beta Grain Structure in a Metastable Beta Titanium Alloy Through Multiple Forging-Annealing Cycles
A coarse-grained (order of 1 mm) Ti-5553 metastable beta alloy was subjected to multiple passes of low-temperature forging and multiple forging plus annealing cycles, respectively. In the forging only processi...
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Article
Transformation of Lamellar Structures in Equal Channel Angular Pressing: Geometric Model and Application to Nickel Aluminum Bronze
Nickel aluminum bronze (NAB) with a duplex structure was subjected to equal channel angular pressing (ECAP). Samples were pressed for up to four passes at 673 K (400 °C) using routes A, BA, BC, and C, respectivel...
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Article
Open AccessUncovering co-expression gene network modules regulating fruit acidity in diverse apples
Acidity is a major contributor to fruit quality. Several organic acids are present in apple fruit, but malic acid is predominant and determines fruit acidity. The trait is largely controlled by the Malic acid (Ma
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Article
A co-expression gene network associated with developmental regulation of apple fruit acidity
Apple fruit acidity, which affects the fruit’s overall taste and flavor to a large extent, is primarily determined by the concentration of malic acid. Previous studies demonstrated that the major QTL malic acid (
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Article
Towards an improved apple reference transcriptome using RNA-seq
The reference genome of apple (Malus × domestica) has been available since 2010. Despite being a milestone in apple genomics, the reference genome is difficult to be used as a reference in RNA-seq (RNA sequencin...
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Article
Effect of Equal Channel Angular Pressing on Lamellar Microstructures in Nickel Aluminum Bronze
A lamellar nickel aluminum bronze has been processed by equal channel angular pressing (ECAP) and its microstructure investigated. The orientation, spacing, and morphology of the lamellae after ECAP were obser...
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Article
Significantly enhanced tensile strength and ductility in nickel aluminium bronze by equal channel angular pressing and subsequent heat treatment
Nickel aluminium bronze (NAB) was subjected to equal channel angular pressing (ECAP) at 400 °C for up to 4 passes in routes BA and C, respectively, followed by isothermal heat treatment with a view to improving t...
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Article
A natural mutation-led truncation in one of the two aluminum-activated malate transporter-like genes at the Ma locus is associated with low fruit acidity in apple
Acidity levels greatly affect the taste and flavor of fruit, and consequently its market value. In mature apple fruit, malic acid is the predominant organic acid. Several studies have confirmed that the major ...
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Article
Genetic characterization of the Ma locus with pH and titratable acidity in apple
Apple fruit flavor is greatly affected by the level of malic acid, which is the major organic acid in mature apple fruit. To understand the genetic and molecular basis of apple fruit acidity, fruit juice pH an...
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Article
Fine genetic map** of the Co locus controlling columnar growth habit in apple
Tree architecture is an important, complex and dynamic trait affected by diverse genetic, ontogenetic and environmental factors. ‘Wijcik McIntosh’, a columnar (reduced branching) sport of ‘McIntosh’ and a valu...
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Article
EST contig-based SSR linkage maps for Malus × domestica cv Royal Gala and an apple scab resistant accession of M. sieversii, the progenitor species of domestic apple
Malus sieversii is a progenitor species of domestic apple M. × domestica. Using population “GMAL 4595” of 188 individuals derived from a cross of Royal Gala × PI 613988 (apple scab resist...
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Article
Open AccessA new implementation of high-throughput five-dimensional clone pooling strategy for BAC library screening
A five-dimensional (5-D) clone pooling strategy for screening of bacterial artificial chromosome (BAC) clones with molecular markers utilizing highly-parallel Illumina GoldenGate assays and PCR facilitates hig...
