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  1. No Access

    Article

    Influence of the aldehyde dehydrogenase 2 polymorphism on the vasodilatory effect of nitroglycerin in infants with congenital heart disease and pulmonary arterial hypertension

    The influence of the aldehyde dehydrogenase 2 (ALDH2) gene polymorphism on the pharmacokinetics and haemodynamics of nitroglycerin (GTN) was determined in human subjects.

    Tatsuya Nagano, Kentaro Ushijima, Naoyuki Taga… in European Journal of Clinical Pharmacology (2019)

  2. No Access

    Article

    Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling

    We recently isolated a Krüppel-like zinc-finger transcription factor 5 (KLF5; also known as BTEB2 and IKLF), which is markedly induced in activated vascular smooth-muscle cells and fibroblasts. Here we describ...

    Takayuki Shindo, Ichiro Manabe, Yasushi Fukushima, Kazuyuki Tobe… in Nature Medicine (2002)