5,811 Result(s)
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Article
Nonspecific influx of cytotoxic T cells into influenza virus-infected lungs of mice
The influx of cytotoxic T cells into A/WSN influenza virus-infected mouse lungs was investigated by adoptive transfer with [125I]5-iodo-2′-deoxyuridine ([125I]UdR)-labeled syngeneic cells. More A/WSN virus-immune...
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Article
Effect of l-tetrahydropalmatine on dopamine release and metabolism in the rat striatum
In vivo voltammetric measurements of striatal extracellular DOPAC concentrations and of striatal DA release in combination with post-mortem analysis of striatal catechols were performed in the rat to study the...
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Chapter
The Effects of High and Low Chromium Yeast Supplementation on Glucose Metabolism of Noninsulin Dependent Diabetic Patients
Chromium in the trivalent state is an essential element required for normal carbohydrate and lipid metabolism; in the form of hexavalent compounds it is a carcinogen. Chromium deficient animals display impaire...
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Chapter and Conference Paper
Reactions in the Presence of Cyclodextrins
The bromination of toluene and the oxidation of α-pinene were studied in presence of cyclodextrins. The bromination reaction has been carried out in acetic acid of different concentrations at different tempera...
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Article
Size Characterization of Mycobacterium bovis BCG (Bacillus Calmette Guérin) Vaccine, Tice™ Substrain
Reconstituted, lyophilized, attenuated Mycobacterium bovis, Bacillus Calmette Guérin (BCG) vaccine, Tice™ substrain, was characterized using a Coulter Multisizer and a HIAC/Royco counter. The primary organism ...
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Article
Clinical manifestations and diagnosis of acute pyrethroid poisoning
This article reviews 573 cases of acute pyrethroid poisoning reported in the Chinese medical literatures during 1983–1988. There were 325 cases of acute deltamethrin poisoning (occupational 158, accidental 167...
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Article
Clozapine in China: a review and preview of US/PRC collaboration
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Chapter
Immunological Methods for the Detection of Polycyclic Aromatic Hydrocarbon-DNA and Protein Adducts
Sensitive immunological methods are now available for the detection and quantitation of carcinogen-DNA and protein adducts. Both monoclonal and polyclonal antibodies have been developed against DNA modified by...
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Chapter
Paradoxical Effects of Vitamin E: Oxidized Lipoproteins, Prostanoids and the Pathogenesis of Atherosclerosis
Sixty years ago Michel Macheboeuf published his Doctor of Science Thesis and a year later his first paper on the isolation of a lipoprotein from horse serum. His outstanding studies1 showed for the first time tha...
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Chapter
Traditions of Antihypertensive Therapy in Different Countries
The therapy of hypertension has evolved over the past 50 years from the short-term care of a small number of hospitalized patients with severely elevated blood pressure and organ damage to a major community he...
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Article
Interactions of 7-[3-(4-[2,3-Dimethylphenyl]piperazinyl)-propoxy]-2(lH)-quinolinone (OPC-4392) with 3H-Spiperone and 3H-SCH 23390 Binding in Rat Striatum: Effects of Lesions
7-[3-(4-[2,3-Dimethylphenyl]piperazinyl)propoxy]-2(lH)-quinolinone (OPC-4392), a presynaptic dopamine autoreceptor agonist and postsynaptic D-2 receptor antagonist (Yasuda et al, Life Sci. 42:1941–1954,1988), was...
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Article
Protection against cisplatin-induced lipid peroxidation and kidney damage by procaine in rats
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Chapter
Effects of Pinacidil, Cromakalim, and Nicorandil on Potassium Currents of Rat Basilar Artery Smooth Muscle
Pinacidil, nicorandil, and cromakalim are antihypertensive agents, which relax peripheral vascular smooth muscle by hyperpolarizing smooth muscle cells towards the potassium equilibrium potential (Weir and Wes...
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Chapter
Pharmacokinetic Parameter Estimation with Stochastic Dynamic Models
The pharmacokinetic parameter estimation problem is reexamined within the framework of stochastic dynamic systems. Using this formalism, two sources of uncertainty are incorporated into the parameter estimatio...
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Chapter
The Differential Expression Pattern of the mRNAs Encoding β Subunits (β 1 , β 2 and β 3) of GABAA Receptor in Rat Brain
Gamma-aminobutyric acid (GABA) is a well known major inhibitory neurotransmitter in the vertebrate brain. Its inhibitory action is mediated through the activation of the specific receptors: the GABAA and GABAB re...
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Article
Bead Coating. I. Change in Release Kinetics (and Mechanism) Due to Coating Levels
Beads containing 50% acetaminophen (APAP) and 50% microcrystalline cellulose (Avicel PH 101) were prepared and then coated using an aqueous ethylcellulose based dispersion (Aquacoat) to evaluate the effect of ...
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Article
In Vitro and in Vivo Investigations of Dihydropyridine-Based Chemical Delivery Systems for Anticonvulsants
A dihydropyridine-based chemical delivery system (CDS), intended to improve drug delivery to the brain, was investigated with a series of analogues of the anticonvulsant stiripentol. In vitro experiments demonstr...
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Article
Unusual effects of SCN and lyotropic anions on contractility of vascular smooth muscle from female rats
Replacement of extracellular chloride ions by thiocyanate anions (SCN−) followed by washout in normal chloride-containing solution produced contractions in isolated rat aortas and portal veins of female rats foll...
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Article
Misoprostol attenuates acetic acid-induced damage in rabbit distal small intestine
The influence of misoprostol pretreatment (100 μg/loop intraluminally) on small intestinal damage induced by acetic acid was evaluated in anesthetized rabbits. In this model injury was induced by intraluminal ...
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Article
Histamine is a transient marker of small intestinal injury induced by luminal acetic acid and casein
We compared the time course of histamine release with other markers of intestinal injury in a rabbit model of necrotizing enterocolitis. Injury was induced by luminal acetic acid (200 mM) and casein (10 mg/ml) an...
