124 Result(s)
within
Kazuo Nishimura
English
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Article
Knowledge-based structural change
How will structural change unfold beyond the rise of services? Motivated by the observed dynamics within the service sector we propose a model of structural change in which productivity is endogenous and outpu...
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Article
Open AccessThe prognostic impact of peripheral blood eosinophil counts in metastatic renal cell carcinoma patients treated with nivolumab
Although immune checkpoint inhibitors (ICIs) have gained approval for metastatic renal cell carcinoma (mRCC), the response rate is still limited. Therefore, it is urgent to explore novel markers of responses t...
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Article
Expectations, beliefs and the business cycle: tracing back to the deep economic drivers
When can exogenous changes in beliefs generate endogenous fluctuations in rational expectation models? We analyze this question in the canonical one-sector and two-sector models of the business cycle with incr...
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Article
Relapsing cytokine release syndrome in a patient with metastatic renal cell carcinoma treated with pembrolizumab and axitinib therapy
As immune checkpoint inhibitors become more widely available, the optimal management of immune-related adverse events (irAEs) is becoming increasingly important. Although irAEs are diverse, reports on cytokine...
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Article
Open AccessParenting methods in relation to norm awareness, social success, and perspectives of family in adulthood
The importance of parenting methods applied in the home to child development is broadly acknowledged. However, there has not been much empirical research showing how parenting methods later relate to personali...
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Article
Management of bone metastasis in prostate cancer
Progression of bone metastases is the primary cause of death in prostate cancer, and skeletal-related events (SREs), including pathologic fractures, spinal cord compression, radiation, or surgery to bone can i...
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Article
Open AccessA phase II randomized trial of metastasis-directed therapy with alpha emitter radium-223 in men with oligometastatic castration-resistant prostate cancer (MEDAL)
The significance of metastasis-directed therapy for oligometastatic prostate cancer has been widely discussed, and targeted therapy for progressive sites is a feasible option as a multidisciplinary treatment f...
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Article
Open AccessFinal efficacy and safety results and biomarker analysis of a phase 2 study of cabozantinib in Japanese patients with advanced renal cell carcinoma
Cabozantinib was established as the standard of care for the treatment of patients with renal cell carcinoma (RCC) whose disease had progressed after vascular endothelial growth factor receptor tyrosine kinase...
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Article
Flying or trapped?
We develop a unified theory with endogenous technology choice in human/knowledge capital accumulation to obtain a rich array of development paradigms. The transition from a less productive technology to a more...
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Article
Real-world efficacy and safety of nivolumab plus ipilimumab in untreated metastatic renal cell carcinoma, and the impact of previous nephrectomy on clinical outcome: Japanese multi-institutional retrospective study
In metastatic renal-cell carcinoma (mRCC), recent clinical trials have shown efficacy of first-line combination therapy, as evidenced by better clinical outcome over target therapy. However, there are insuffic...
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Article
Open AccessJapan’s R&D capabilities have been decimated by reduced class hours for science and math subjects
The number of published scientific papers and patent applications are indicators of a country’s research and development (R&D) capabilities. Since the 2010s, these indicators have declined in Japan. One import...
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Article
Open AccessCorrection to: Real-world use of enzalutamide in men with nonmetastatic castration-resistant prostate cancer in Japan
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Article
Open AccessWhole-body MRI: detecting bone metastases from prostate cancer
Whole-body magnetic resonance imaging (WB-MRI) is currently used worldwide for detecting bone metastases from prostate cancer. The 5-year survival rate for prostate cancer is > 95%. However, an increase in sur...
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Article
Open AccessReal-world use of enzalutamide in men with nonmetastatic castration-resistant prostate cancer in Japan
The purpose of the study is to evaluate real-world effectiveness and safety of enzalutamide in men with nonmetastatic castration-resistant prostate cancer (nmCRPC) in Japan.
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Chapter
Education Policy and Behavioral Change in Science Learning—An Empirical Analysis Based on Japanese Data
The study of science subjects in school education is important for the advancement of science and technology. However, it is true that many students avoid science and mathematics. The significance of examining...
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Chapter
Life and Workplace Satisfaction and Behaviour Change Ability—An Empirical Study in Japan
This paper analyzes the attributes that would cause behaviour change based on responses to questions about behaviour change, examines how satisfaction with their life is associated with the respondents’ behavi...
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Article
The prognostic impact of immune-related adverse events in metastatic renal cell carcinoma patients treated with nivolumab: a real-world multi-institutional retrospective study
Recent studies have shown that immune-related adverse events (irAEs) caused by immune checkpoint inhibitors (ICIs) were correlated with favorable clinical outcome in patients with melanoma. However, in metasta...
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Article
Antiresorptive agent-related osteonecrosis of the jaw in prostate cancer patients with bone metastasis treated with bone-modifying agents
The incidence rate and risk factors of antiresorptive agent-related osteonecrosis of the jaw (ARONJ) in prostate cancer patients with bone metastasis are not clear.
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Time and Mnemonic Morphism
chapter provides a theoretic formulation for the relationship of the conscious (cognitive) states of an for the , , in terms of nonfunctorially induced mnemonic morphisms. The is recalled by , and ...
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Chapter
Correction to: David Pines and Me
