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  1. No Access

    Article

    A patient with esophageal cancer with bone metastasis who achieved pain relief with repetitive administration of strontium-89 chloride

    A 75-year-old woman was diagnosed with esophageal cancer with difficulty in swallowing. She had a past history of rheumatoid arthritis, scleroderma, interstitial pneumonia, angina pectoris (with coronary arter...

    Osamu Maeda, Takafumi Ando, Kazuhiro Ishiguro in Clinical Journal of Gastroenterology (2014)

  2. No Access

    Article

    Quantitative diagnosis of chronic pancreatitis using EUS elastography

    It is difficult to diagnose chronic pancreatitis (CP) objectively because of a lack of standard diagnostic criteria. Endoscopic ultrasonography (EUS) has been used to assess the severity of CP, but the diagnos...

    Takamichi Kuwahara, Yoshiki Hirooka, Hiroki Kawashima in Journal of Gastroenterology (2017)

  3. No Access

    Article

    Prognostic impact of PD-L1 expression in primary gastric and intestinal diffuse large B-cell lymphoma

    Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease and the most common gastrointestinal lymphoma. The prognostic/predictive indicators among patients with gastric and intestinal DLBCL (giDLBCL) a...

    Eri Ishikawa, Masanao Nakamura, Kazuyuki Shimada in Journal of Gastroenterology (2020)

  4. Article

    Open Access

    Use of Immunostaining for the diagnosis of Lymphovascular invasion in superficial Barrett’s esophageal adenocarcinoma

    The prevalence of Barrett’s esophageal adenocarcinoma (BEA) is increasing in Japan. Accurate assessment of lymphovascular invasion (LVI) after endoscopic resection or surgery is essential in evaluating treatme...

    Isao Hosono, Ryoji Miyahara, Kazuhiro Furukawa, Kohei Funasaka in BMC Gastroenterology (2020)

  5. No Access

    Article

    The microbiome can predict mucosal healing in small intestine in patients with Crohn’s disease

    Mucosal healing is the main treatment goal for Crohn’s disease. In this situation, some patients have difficulty with endoscopic evaluation of the entire small intestine. Crohn’s disease is closely associated ...

    Shun Hattori, Masanao Nakamura, Takeshi Yamamura in Journal of Gastroenterology (2020)

  6. No Access

    Article

    Ustekinumab is effective against small bowel lesions in Crohn’s disease: two case reports

    We encountered two patients with Crohn’s disease (CD) for whom induction of ustekinumab was effective for the management of small intestinal lesions with stenosis. The first symptomatic CD case was a 40-year-o...

    Kentaro Murate, Masanao Nakamura, Takeshi Yamamura in Clinical Journal of Gastroenterology (2021)

  7. Article

    Open Access

    Diagnostic yield of colon capsule endoscopy for Crohn’s disease lesions in the whole gastrointestinal tract

    Crohn’s disease (CD) can involve the upper gastrointestinal (GI) tract as well as the small and large bowel. PillCam colon capsule endoscopy (PCCE-2) enables observation of the whole GI tract, but its diagnost...

    Keisaku Yamada, Masanao Nakamura, Takeshi Yamamura, Keiko Maeda in BMC Gastroenterology (2021)

  8. No Access

    Article

    Filtrated Adipose Tissue-Derived Mesenchymal Stem Cell Lysate Ameliorates Experimental Acute Colitis in Mice

    Inflammatory bowel disease (IBD) is a chronic, persistent, and intractable enteritis; however, an effective treatment strategy is yet to be established. Mesenchymal stem cells (MSCs) and their paracrine factor...

    Takahiro Nishikawa, Keiko Maeda, Masanao Nakamura in Digestive Diseases and Sciences (2021)

  9. No Access

    Article

    New modality for the quantitative evaluation of tissue elasticity using a forward-viewing radial-array echoendoscope for colorectal neoplasms

    Sound speed correction (SSC) is a non-invasive modality that quantifies the hardness of neoplasms. The aim of our study was to evaluate the usefulness of SSC for the diagnostic accuracy of colorectal neoplasms...

    Masaya Esaki, Takeshi Yamamura in International Journal of Colorectal Disease (2021)

  10. Article

    Open Access

    Measurement of fasting breath hydrogen concentration as a simple diagnostic method for pancreatic exocrine insufficiency

    Pancreatic exocrine insufficiency (PEI) is associated with the outcome of pancreatic disease. However, there is no method for assessing PEI that can be used noninvasively and easily for outpatient. It has been...

    Kota Uetsuki, Hiroki Kawashima, Eizaburo Ohno, Takuya Ishikawa in BMC Gastroenterology (2021)

  11. Article

    Open Access

    Immunohistochemical staining for IMP3 in patients with duodenal papilla tumors: assessment of the potential for diagnosing endoscopic resectability and predicting prognosis

    Endoscopic papillectomy of duodenal papillary tumors (PT) is indicated for adenomas or well-differentiated adenocarcinomas that do not involve the sphincter of Oddi. However, there is currently no reliable pre...

    Hiroyuki Tanaka, Hiroki Kawashima, Eizaburo Ohno, Takuya Ishikawa in BMC Gastroenterology (2021)

  12. No Access

    Article

    Subjective Symptoms in Patients with Eosinophilic Esophagitis Are Related to Esophageal Wall Thickness and Esophageal Body Pressure

    Endoscopic ultrasonography (EUS) and high-resolution manometry (HRM) can be used in the evaluation of eosinophilic esophagitis (EoE) for frequent symptoms such as dysphagia. However, the role of these examinat...

    Koichi Muroi, Naomi Kakushima, Kazuhiro Furukawa in Digestive Diseases and Sciences (2021)

  13. No Access

    Article

    A forward-viewing radial-array echoendoscope is useful for diagnosing the depth of colorectal neoplasia invasion

    It is important to accurately diagnose the depth of colorectal neoplasia invasion. We aimed to evaluate the usefulness of a new forward-viewing radial-array echoendoscope (FRE), relative to the pit pattern met...

    Takeshi Kuno, Takeshi Yamamura, Masanao Nakamura, Keiko Maeda in Surgical Endoscopy (2021)

  14. No Access

    Article

    The impact of the age-adjusted Charlson comorbidity index as a prognostic factor for endoscopic papillectomy in ampullary tumors

    The prognostic nutritional index (PNI) and Charlson comorbidity index (CCI) have been useful for predicting the prognosis based on nutritional condition and comorbidities in surgery and endoscopic mucosal diss...

    Yoshihisa Takada, Hiroki Kawashima, Eizaburo Ohno in Journal of Gastroenterology (2022)

  15. Article

    Artificial intelligence-based diagnosis of upper gastrointestinal subepithelial lesions on endoscopic ultrasonography images

    Endoscopic ultrasonography (EUS) is useful for the differential diagnosis of subepithelial lesions (SELs); however, not all of them are easy to distinguish. Gastrointestinal stromal tumors (GISTs) are the comm...

    Keiko Hirai, Takamichi Kuwahara, Kazuhiro Furukawa, Naomi Kakushima in Gastric Cancer (2022)

  16. Article

    Open Access

    Endoscopic sphincterotomy and endoscopic biliary stenting do not affect the sensitivity of transpapillary forceps biopsy for the diagnosis of bile duct adenocarcinoma

    The pathological evaluation of tissues with cholangitis is considered difficult, which can often occur after endoscopic sphincterotomy (EST) and endoscopic biliary stenting (EBS). This study aimed to evaluate ...

    Toshinori Aoki, Eizaburo Ohno, Takuya Ishikawa, Yasuyuki Mizutani in BMC Gastroenterology (2022)

  17. Article

    Open Access

    Fecal microbiota transplantation in the treatment of irritable bowel syndrome: a single-center prospective study in Japan

    Fecal microbiota transplantation (FMT) is a potential treatment for irritable bowel syndrome (IBS), but its efficacy in Japanese IBS patients is unknown. This study aimed to evaluate the efficacy, side effects...

    Motonobu Hamazaki, Tsunaki Sawada, Takeshi Yamamura, Keiko Maeda in BMC Gastroenterology (2022)

  18. No Access

    Article

    Comparison of outcomes between secondary fully covered and uncovered self-expandable metal stents in the treatment of recurrent biliary obstruction of pancreatic cancer

    The overall survival (OS) of pancreatic cancer (PC) has been prolonged by advances in chemotherapy, and the number of cases of recurrent biliary obstruction (RBO) after self-expandable metal stent (SEMS) place...

    Kunio Kataoka, Hiroki Kawashima, Eizaburo Ohno, Takuya Ishikawa in Surgical Endoscopy (2022)

  19. No Access

    Article

    Novel endoscopic approaches using the endocytoscopy for the target biopsy in esophageal eosinophilia

    Multiple biopsies are recommended for the diagnosis of eosinophilic esophagitis (EoE) because inflammatory changes are frequently patchy. Reports on EoE using endocytoscopy (ECS) are limited. This present stud...

    Koichi Muroi, Naomi Kakushima, Kazuhiro Furukawa, Satoshi Furune, Nobuhito Ito in Esophagus (2023)

  20. Article

    Open Access

    Clinical characteristics of Dieulafoy’s lesion in the small bowel diagnosed and treated by double-balloon endoscopy

    Obscure gastrointestinal bleeding refers to bleeding for which the source cannot be ascertained even through balloon-assisted endoscopy. In certain instances, Dieulafoy’s lesion in the small bowel is presumed ...

    Masanao Nakamura, Takeshi Yamamura, Keiko Maeda, Tsunaki Sawada in BMC Gastroenterology (2023)

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