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  1. Article

    Open Access

    Bacterial vesicles block viral replication in macrophages via TLR4-TRIF-axis

    Gram-negative bacteria naturally secrete nano-sized outer membrane vesicles (OMVs), which are important mediators of communication and pathogenesis. OMV uptake by host cells activates TLR signalling via transp...

    Jeff Bierwagen, Marie Wiegand, Katrin Laakmann in Cell Communication and Signaling (2023)

  2. Article

    Open Access

    Bacterial extracellular vesicles repress the vascular protective factor RNase1 in human lung endothelial cells

    Sepsis is one of the leading causes of death worldwide and characterized by blood stream infections associated with a dysregulated host response and endothelial cell (EC) dysfunction. Ribonuclease 1 (RNase1) a...

    Katrin Laakmann, Jorina Mona Eckersberg, Moritz Hapke in Cell Communication and Signaling (2023)