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Highly Halogenated Tetrahydro-β-Carbolines as a New Class of Dopaminergic Neurotoxins

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  1. Article

    Open Access

    Alterations of nocturnal activity in rats following subchronic oral administration of the neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline

    1-Trichloromethyl-1,2,3,4-tetrahydro-β-carboline (TaClo) is neurotoxic when administered to the brain and alters motor behaviour following intraperitoneal administration. We have assessed the long-term effects...

    Thomas A. Sontag, Klaus W. Lange, Christine Heim… in Journal of Neural Transmission (2009)

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  2. Article

    The analysis system COGITAT for the study of cognitive deficiencies in rodents

    COGITAT is an automated hole board system that, following minimal experimental interventions, makes it possible to measure a variety of parameters associated with learning, memory, relearning, cognition, and c...

    Christine Heim, Iancu Pardowitz… in Behavior Research Methods, Instruments, & … (2000)

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