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  1. Article

    Correction to: Characterization of novel pollen-expressed transcripts reveals their potential roles in pollen heat stress response in Arabidopsis thaliana

    After publication of the article we found that the Fig. 7

    Nicholas Rutley, Laetitia Poidevin, Tirza Doniger, Richard L. Tillett in Plant Reproduction (2021)

  2. Article

    Open Access

    Characterization of novel pollen-expressed transcripts reveals their potential roles in pollen heat stress response in Arabidopsis thaliana

    Arabidopsis pollen transcriptome analysis revealed new intergenic transcripts of unknown function, many of which are long non-coding RNAs, that may function in pollen-specific processes, including the heat stress...

    Nicholas Rutley, Laetitia Poidevin, Tirza Doniger, Richard L. Tillett in Plant Reproduction (2021)

  3. Article

    Open Access

    Drought tolerance of the grapevine, Vitis champinii cv. Ramsey, is associated with higher photosynthesis and greater transcriptomic responsiveness of abscisic acid biosynthesis and signaling

    Grapevine is an economically important crop for which yield and berry quality is strongly affected by climate change. Large variations in drought tolerance exist across Vitis species. Some of these species are us...

    Noé Cochetel, Ryan Ghan, Haley S. Toups, Asfaw Degu in BMC Plant Biology (2020)

  4. Article

    Open Access

    Genome-wide rare variant analysis for thousands of phenotypes in over 70,000 exomes from two cohorts

    Understanding the impact of rare variants is essential to understanding human health. We analyze rare (MAF < 0.1%) variants against 4264 phenotypes in 49,960 exome-sequenced individuals from the UK Biobank and...

    Elizabeth T. Cirulli, Simon White, Robert W. Read, Gai Elhanan in Nature Communications (2020)

  5. No Access

    Article

    Single-nucleotide polymorphisms in a cohort of significantly obese women without cardiometabolic diseases

    Obesity is an important risk factor for the development of diseases such as diabetes mellitus, hypertension, and dyslipidemia; however, a small number of individuals with long-standing obesity do not present w...

    Karen A. Schlauch, Doina Kulick in International Journal of Obesity (2019)

  6. Article

    Open Access

    Evaluation of four clinical laboratory parameters for the diagnosis of myalgic encephalomyelitis

    Myalgic encephalomyelitis (ME) is a complex and debilitating disease that often initially presents with flu-like symptoms, accompanied by incapacitating fatigue. Currently, there are no objective biomarkers or...

    Kenny L. De Meirleir, Tatjana Mijatovic in Journal of Translational Medicine (2018)

  7. Article

    Open Access

    A comparison of heat-stress transcriptome changes between wild-type Arabidopsis pollen and a heat-sensitive mutant harboring a knockout of cyclic nucleotide-gated cation channel 16 (cngc16)

    In flowering plants, the male gametophyte (pollen) is one of the most vulnerable cells to temperature stress. In Arabidopsis thaliana, a pollen-specific Cyclic Nucleotide-Gated cation Channel 16 (cngc16), is requ...

    Maryam Rahmati Ishka, Elizabeth Brown, Chrystle Weigand, Richard L. Tillett in BMC Genomics (2018)

  8. Article

    Open Access

    Humoral Immunity Profiling of Subjects with Myalgic Encephalomyelitis Using a Random Peptide Microarray Differentiates Cases from Controls with High Specificity and Sensitivity

    Myalgic encephalomyelitis (ME) is a complex, heterogeneous illness of unknown etiology. The search for biomarkers that can delineate cases from controls is one of the most active areas of ME research; however,...

    Sahajpreet Singh, Phillip Stafford, Karen A. Schlauch in Molecular Neurobiology (2018)

  9. Article

    Open Access

    The common transcriptional subnetworks of the grape berry skin in the late stages of ripening

    Wine grapes are important economically in many countries around the world. Defining the optimum time for grape harvest is a major challenge to the grower and winemaker. Berry skins are an important source of f...

    Ryan Ghan, Juli Petereit, Richard L. Tillett, Karen A. Schlauch in BMC Plant Biology (2017)

  10. Article

    Open Access

    Sporobolus stapfianus: Insights into desiccation tolerance in the resurrection grasses from linking transcriptomics to metabolomics

    Understanding the response of resurrection angiosperms to dehydration and rehydration is critical for deciphering the mechanisms of how plants cope with the rigors of water loss from their vegetative tissues. ...

    Abou Yobi, Karen A. Schlauch, Richard L. Tillett, Won C. Yim in BMC Plant Biology (2017)

  11. Article

    Open Access

    petal: Co-expression network modelling in R

    Networks provide effective models to study complex biological systems, such as gene and protein interaction networks. With the advent of new sequencing technologies, many life scientists are gras** for user-...

    Juli Petereit, Sebastian Smith, Frederick C. Harris Jr in BMC Systems Biology (2016)

  12. Article

    Open Access

    Transcriptomic network analyses of leaf dehydration responses identify highly connected ABA and ethylene signaling hubs in three grapevine species differing in drought tolerance

    Grapevine is a major food crop that is affected by global climate change. Consistent with field studies, dehydration assays of grapevine leaves can reveal valuable information of the plant’s response at physio...

    Daniel W. Hopper, Ryan Ghan, Karen A. Schlauch, Grant R. Cramer in BMC Plant Biology (2016)

  13. Article

    Open Access

    Abscisic acid transcriptomic signaling varies with grapevine organ

    Abscisic acid (ABA) regulates various developmental processes and stress responses over both short (i.e. hours or days) and longer (i.e. months or seasons) time frames. To elucidate the transcriptional regulat...

    Supakan Rattanakon, Ryan Ghan, Gregory A. Gambetta, Laurent G. Deluc in BMC Plant Biology (2016)

  14. Article

    Open Access

    Five omic technologies are concordant in differentiating the biochemical characteristics of the berries of five grapevine (Vitis vinifera L.) cultivars

    Grape cultivars and wines are distinguishable by their color, flavor and aroma profiles. Omic analyses (transcripts, proteins and metabolites) are powerful tools for assessing biochemical differences in biolog...

    Ryan Ghan, Steven C. Van Sluyter, Uri Hochberg, Asfaw Degu in BMC Genomics (2015)

  15. Article

    Open Access

    Transcriptomic analysis of the late stages of grapevine (Vitis vinifera cv. Cabernet Sauvignon) berry ripening reveals significant induction of ethylene signaling and flavor pathways in the skin

    Grapevine berry, a nonclimacteric fruit, has three developmental stages; the last one is when berry color and sugar increase. Flavors derived from terpenoid and fatty acid metabolism develop at the very end of...

    Grant R Cramer, Ryan Ghan, Karen A Schlauch, Richard L Tillett in BMC Plant Biology (2014)

  16. Article

    Open Access

    Identification of tissue-specific, abiotic stress-responsive gene expression patterns in wine grape (Vitis viniferaL.) based on curation and mining of large-scale EST data sets

    Abiotic stresses, such as water deficit and soil salinity, result in changes in physiology, nutrient use, and vegetative growth in vines, and ultimately, yield and flavor in berries of wine grape, Vitis vinifera ...

    Richard L Tillett, Ali Ergül, Rebecca L Albion, Karen A Schlauch in BMC Plant Biology (2011)

  17. No Access

    Chapter

    Transcriptomics Analysis Methods: Microarray Data Processing, Analysis and Visualization Using the Affymetrix Genechip® Vitis Vinifera Genome Array

    The study of transcriptomics is a powerful method of studying the responses of organisms to their environment. The transcriptome consists of the entire set of transcripts that are expressed within a cell or or...

    Karen A. Schlauch, Jerome Grimplet in Methodologies and Results in Grapevine Res… (2010)

  18. Article

    Open Access

    Water deficit alters differentially metabolic pathways affecting important flavor and quality traits in grape berries of Cabernet Sauvignon and Chardonnay

    Water deficit has significant effects on grape berry composition resulting in improved wine quality by the enhancement of color, flavors, or aromas. While some pathways or enzymes affected by water deficit hav...

    Laurent G Deluc, David R Quilici, Alain Decendit, Jérôme Grimplet in BMC Genomics (2009)

  19. Article

    Open Access

    Transcriptomic and metabolite analyses of Cabernet Sauvignon grape berry development

    Grape berry development is a dynamic process that involves a complex series of molecular genetic and biochemical changes divided into three major phases. During initial berry growth (Phase I), berry size incre...

    Laurent G Deluc, Jérôme Grimplet, Matthew D Wheatley, Richard L Tillett in BMC Genomics (2007)

  20. No Access

    Article

    Transcript abundance profiles reveal larger and more complex responses of grapevine to chilling compared to osmotic and salinity stress

    Cabernet Sauvignon grapevines were exposed to sudden chilling (5°C), water deficit (PEG), and an iso-osmotic salinity (120 mM NaCl and 12 mM CaCl2) for 1, 4, 8, and 24 h. Stomatal conductance and stem water poten...

    Elizabeth A. R. Tattersall, Jérôme Grimplet in Functional & Integrative Genomics (2007)

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