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Article
Deep learning-based prediction model for postoperative complications of cervical posterior longitudinal ligament ossification
Postoperative complication prediction helps surgeons to inform and manage patient expectations. Deep learning, a model that finds patterns in large samples of data, outperform traditional statistical methods i...
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Article
Open AccessExpression of proinflammatory cytokines and proinsulin by bone marrow-derived cells for fracture healing in long-term diabetic mice
Diabetes mellitus (DM) causes bone dysfunction due to poor bone quality, leading to severe deterioration in patient of quality of life. The mechanisms of bone metabolism in DM remain unclear, although chemical...
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Article
Open AccessComparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis: a multicenter study
To evaluate the radiological differences between diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) using whole spine computed tomography (CT), including the spine and sacroiliac j...
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Article
Open AccessImpact of obesity on cervical ossification of the posterior longitudinal ligament: a nationwide prospective study
Positive association between ossification of the posterior longitudinal ligament of the spine (OPLL) and obesity is widely recognized; however, few studies focused on the effects of obesity on treatment of cer...
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Article
Open AccessComparison of laminoplasty and posterior fusion surgery for cervical ossification of posterior longitudinal ligament
This prospective multicenter study, established by the Japanese Ministry of Health, Labour and Welfare and involving 27 institutions, aimed to compare postoperative outcomes between laminoplasty (LM) and poste...
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Article
Open AccessThe impact of ossification spread on cervical spine function in patients with ossification of the posterior longitudinal ligament
Ossification of the posterior longitudinal ligament (OPLL) is a progressive disease. The bridging of ossified lesions to the vertebral body gradually increases, thereby decreasing the mobility of the cervical ...
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Article
Open AccessNeurological improvement is associated with neck pain attenuation after surgery for cervical ossification of the posterior longitudinal ligament
Although favourable surgical outcomes for myelopathy caused by cervical ossification of the posterior longitudinal ligament (OPLL) have been reported, factors significantly associated with post-operative neck ...
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Article
Open AccessPredictors for quality of life improvement after surgery for degenerative cervical myelopathy: a prospective multi-center study
Degenerative cervical myelopathy (DCM) can significantly impair a patient’s quality of life (QOL). In this study, we aimed to identify predictors associated with QOL improvement after surgery for DCM.
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Article
Open AccessPredictors associated with neurological recovery after anterior decompression with fusion for degenerative cervical myelopathy
Anterior decompression with fusion (ADF) has often been performed for degenerative cervical myelopathy (DCM) in patients with poor cervical spine alignment and/or anterior cord compression. We aimed to identif...
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Article
Molecular characteristics and clinical outcomes of elderly patients with IDH-wildtype glioblastomas: comparative study of older and younger cases in Kansai Network cohort
Aging is a known negative prognostic factor in glioblastomas (GBM). Whether particular genetic backgrounds are a factor in poor outcomes of elderly patients with GBM warrants investigation. We aim to elucidate...
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Article
Open AccessClinical characteristics in patients with ossification of the posterior longitudinal ligament: A prospective multi-institutional cross-sectional study
Ossification of the posterior longitudinal ligament (OPLL) can occur throughout the entire spine and can sometimes lead to spinal disorder. Although patients with OPLL sometimes develop physical limitations be...
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Chapter
Diagnostic Imaging of Thoracic OPLL and OLF
The most standard diagnostic imaging modality for ossification of the posterior longitudinal ligament of the spine (OPLL) and ossification of the ligamentum flavum (OLF) is a plain radiography; however, standa...
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Article
Open AccessPrediction of IDH and TERT promoter mutations in low-grade glioma from magnetic resonance images using a convolutional neural network
Identification of genotypes is crucial for treatment of glioma. Here, we developed a method to predict tumor genotypes using a pretrained convolutional neural network (CNN) from magnetic resonance (MR) images ...
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Article
Open AccessRadiomics and MGMT promoter methylation for prognostication of newly diagnosed glioblastoma
We attempted to establish a magnetic resonance imaging (MRI)-based radiomic model for stratifying prognostic subgroups of newly diagnosed glioblastoma (GBM) patients and predicting O (6)-methylguanine-DNA meth...
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Article
Open AccessDistribution differences in prognostic copy number alteration profiles in IDH-wild-type glioblastoma cause survival discrepancies across cohorts
The diagnosis and prognostication of glioblastoma (GBM) remain to be solely dependent on histopathological findings and few molecular markers, despite the clinical heterogeneity in this entity. To address this...
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Chapter and Conference Paper
Impacts of the New Carbon Fusion Cross Sections on Type Ia Supernovae
Recent measurement of cross sections of the carbon fusion reaction unveiled existence of low-energy resonances, which enhances reaction rates. We apply the new resonant reaction rates to the double degenerate ...
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Article
Open AccessCharacteristics and outcomes of elderly patients with diffuse gliomas: a multi-institutional cohort study by Kansai Molecular Diagnosis Network for CNS Tumors
This study investigates the current state of clinical practice and molecular analysis for elderly patients with diffuse gliomas and aims to elucidate treatment outcomes and prognostic factors of patients with ...
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Article
Open AccessLesion location implemented magnetic resonance imaging radiomics for predicting IDH and TERT promoter mutations in grade II/III gliomas
Molecular biological characterization of tumors has become a pivotal procedure for glioma patient care. The aim of this study is to build conventional MRI-based radiomics model to predict genetic alterations w...
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Article
Open AccessDistribution of ossified spinal lesions in patients with severe ossification of the posterior longitudinal ligament and prediction of ossification at each segment based on the cervical OP index classification: a multicenter study (JOSL CT study)
In patients with ossification of the posterior longitudinal ligament (OPLL) in the cervical spine, it is well known that the thoracic ossified lesions often coexist with the cervical lesions and can cause seve...
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Chapter and Conference Paper
Clip** of Recurrent Cerebral Aneurysms After Coil Embolization
Background and aims. To assess the technical points of surgical clip** for recurrent aneurysms after coiling, we examine a consecutive series of 14 patients who underwent re-treatment.
