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Optimized combination of Cervus nippon (Sika deer), Angelica (Dangui), and Rehmannia (Suk-jihwang) mitigates LPS-induced inflammation: exploring signaling pathways through plasma metabolomics

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  1. Article

    Open Access

    p53 activation enhances the sensitivity of non-small cell lung cancer to the combination of SH003 and docetaxel by inhibiting de novo pyrimidine synthesis

    Identifying molecular biomarkers for predicting responses to anti-cancer drugs can enhance treatment precision and minimize side effects. This study investigated the novel cancer-targeting mechanism of combini...

    Yu-Jeong Choi, Kangwook Lee, Seo Yeon Lee, Youngbin Kwon… in Cancer Cell International (2024)

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  2. Article

    Open Access

    Network pharmacology study to explore the multiple molecular mechanism of SH003 in the treatment of non-small cell lung cancer

    Non-small cell lung cancer (NSCLC) is one of the leading causes of human death worldwide. Herbal prescription SH003 has been developed to treat several cancers including NSCLC. Due to the multi-component natur...

    Kangwook Lee, Yu-Jeong Choi, Hae-In Lim… in BMC Complementary Medicine and Therapies (2024)

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