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Article
Flavivirus NS1 protein in infected host sera enhances viral acquisition by mosquitoes
The arbovirus life cycle involves viral transfer between a vertebrate host and an arthropod vector, and acquisition of virus from an infected mammalian host by a vector is an essential step in this process. He...
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Article
Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes
A mutation that increases the secretion of Zika virus non-structural protein 1 (NS1) in infected hosts enhances the ability of the virus to infect its mosquito vector Aedes aegypti and might have contributed to t...
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Article
Host serum iron modulates dengue virus acquisition by mosquitoes
A blood meal is the primary route through which mosquitoes acquire an arbovirus infection. Blood components or their metabolites may regulate the susceptibility of mosquitoes to arboviruses. Here we report tha...
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Article
Open AccessA mosquito salivary protein promotes flavivirus transmission by activation of autophagy
Transmission from an infected mosquito to a host is an essential process in the life cycle of mosquito-borne flaviviruses. Numerous studies have demonstrated that mosquito saliva facilitates viral transmission...