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  1. Article

    Open Access

    Safety and efficacy of irinotecan, oxaliplatin, and capecitabine (XELOXIRI) regimen with or without targeted drugs in patients with metastatic colorectal cancer: a retrospective cohort study

    Five-fluorouracil, folinic acid, oxaliplatin and irinotecan (FOLFOXIRI) regimen is used as the first-line treatment for metastatic colorectal cancer (mCRC). The use of capecitabine, an oral fluoropyrimidine pr...

    **u Liu, Kai Ou, **aoting Ma, Lizhen Gao, Qi Wang, Haizeng Zhang, Lin Yang in BMC Cancer (2022)

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  2. Article

    Open Access

    POLE/POLD1 mutation and tumor immunotherapy

    POLE and POLD1 encode the catalytic and proofreading subunits of DNA polymerase ε and polymerase δ, and play important roles in DNA replication and proofreading. POLE/POLD1 exonuclease domain mutations lead to lo...

    **aoting Ma, Lin Dong, **u Liu, Kai Ou… in Journal of Experimental & Clinical Cancer … (2022)

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  3. No Access

    Article

    A 12-chemokine gene signature is associated with the enhanced immunogram scores and is relevant for precision immunotherapy

    Advances in the understanding of checkpoint blockade immunotherapy have suggested that boosting the cancer-immunity cycle (CIC) can help induce regression of tumors. However, good efficacy only occurs in a sub...

    **ngchen Li, Zhiyi Wan, **u Liu, Kai Ou, Lin Yang in Medical Oncology (2022)