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    Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling

    Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown aetiology for which there are no approved therapeutic options. Patients with PSC display changes in gut microbiota and in ...

    Kai Markus Schneider, Lena Susanna Candels, Johannes R. Hov… in Nature Metabolism (2021)